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dc.contributor.author Khalaf, Roy A.
dc.contributor.author Rayes, Roni
dc.contributor.author Ghasham, Mona
dc.contributor.author El Hajj, Nady
dc.contributor.author Sabbagh, Amira S.
dc.contributor.author Mahfouz, Rami A.
dc.date.accessioned 2018-09-13T10:24:19Z
dc.date.available 2018-09-13T10:24:19Z
dc.date.copyright 2007 en_US
dc.date.issued 2018-09-13
dc.identifier.issn 1879-1166 en_US
dc.identifier.uri http://hdl.handle.net/10725/8456
dc.description.abstract Aim: This study represents the first report on KIR distribution among patients with Familial Mediterranean Fever (FMF). Samples and Methods: We studied 56 unrelated Lebanese FMF patients, had their DNA typed using Sequence Specific Primer (SSP) technique for the presence of 16 KIR gene and pseudogene loci and compared them to the general Lebanese population. Results: In addition to sharing common features with the general population, we the AA genotype was still the most frequent; however, with six new KIR profiles identified. Conclusions: There was no statistically significant distribution of the different KIR genes between the cases (FMF patients) and controls (Lebanese population); however, an increase in the BB genotype was noted leading to an interesting future research question of whether or not KIR genotype is involved in the predisposition to or pathogenesis of FMF. This is the first report that describes the KIR genotypic profile in this important clinical disease. en_US
dc.language.iso en en_US
dc.title 183-P en_US
dc.type Article en_US
dc.description.version Published en_US
dc.title.subtitle KIR genotypic profile in patients with Familial Mediterranean Fever en_US
dc.author.school SAS en_US
dc.author.idnumber 200300427 en_US
dc.author.department Natural Sciences en_US
dc.description.embargo N/A en_US
dc.relation.journal Human Immunology en_US
dc.journal.volume 68 en_US
dc.journal.issue Supplement 1 en_US
dc.article.pages S107 en_US
dc.identifier.doi https://doi.org/10.1016/j.humimm.2007.08.206 en_US
dc.identifier.ctation Mahfouz, R. A., Sabbagh, A. S., El Hajj, N., Ghasham, M., Rayes, R., & Khalaf, R. A. (2007). 183-P: KIR genotypic profile in patients with Familial Mediterranean Fever. Human Immunology, 1(68), S107. en_US
dc.author.email roy.khalaf@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url https://www.researchgate.net/publication/237926552_183-P_KIR_genotypic_profile_in_patients_with_Familial_Mediterranean_Fever en_US
dc.author.affiliation Lebanese American University en_US

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