Extended-spectrum β-lactamase-producing Escherichia coli in wastewaters and refugee camp in Lebanon

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dc.contributor.author Tokajian, Sima
dc.contributor.author Moghnieh, Rima
dc.contributor.author Salloum, Tamara
dc.contributor.author Arabaghian, Harout
dc.contributor.author Alousi, Sahar
dc.contributor.author Moussa, Jennifer
dc.contributor.author Abboud, Edmond
dc.contributor.author Youssef, Souad
dc.contributor.author Husni, Rola
dc.date.accessioned 2018-06-26T09:40:28Z
dc.date.available 2018-06-26T09:40:28Z
dc.date.copyright 2017 en_US
dc.date.issued 2018-06-26
dc.identifier.issn 1746-0921 en_US
dc.identifier.uri http://hdl.handle.net/10725/8100
dc.description.abstract Aim: To evaluate the effects of population influx of refugees on the prevalence of extended-spectrum β-lactamase-producing Escherichia coli in wastewater networks in Lebanon. Materials & methods: Pulsed-field gel electrophoresis, multilocus sequence typing and antibiotic resistance genes typing were performed. Results: 53.1% of isolates recovered from Al-Qaa refugee camp were positive for the tested resistant determinants compared with 49.1% from river effluents. All isolates carried aac(6)-1b and/or aac(3)-II; none carried armA, rmtB, ant(4′)-Iia, aph(3′)-Ia or carbapenemases. CTX-M-15, TEM-1, OXA-1, CMY-2 and SHV-12 were detected. Single and/or double substitutions were detected in GyrA and ParC. Phylogenetic group B2 and ST6470 were the most prevalent. Pulsed-field gel electrophoresis revealed 19 XbaI patterns and 17 pulsotypes. Conclusion: The introduction of novel resistance patterns into the wastewater network requires effective control. en_US
dc.language.iso en en_US
dc.title Extended-spectrum β-lactamase-producing Escherichia coli in wastewaters and refugee camp in Lebanon en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SAS en_US
dc.author.idnumber 199736770 en_US
dc.author.department Natural Sciences en_US
dc.description.embargo N/A en_US
dc.relation.journal Future microbiology en_US
dc.journal.volume 13 en_US
dc.journal.issue 1 en_US
dc.article.pages 81-95 en_US
dc.keywords Antibiotics resistance en_US
dc.keywords ESBLs en_US
dc.keywords Lebanon en_US
dc.keywords MLTS en_US
dc.keywords PFGE en_US
dc.keywords Population migrations en_US
dc.keywords Wastewater en_US
dc.identifier.doi https://doi.org/10.2217/fmb-2017-0093 en_US
dc.identifier.ctation Tokajian, S., Moghnieh, R., Salloum, T., Arabaghian, H., Alousi, S., Moussa, J., ... & Husni, R. (2018). Extended-spectrum β-lactamase-producing Escherichia coli in wastewaters and refugee camp in Lebanon. Future microbiology, 13(1), 81-95. en_US
dc.author.email stokajian@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url https://www.futuremedicine.com/doi/abs/10.2217/fmb-2017-0093 en_US
dc.author.affiliation Lebanese American University en_US

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