| dc.contributor.author |
Tokajian, Sima |
|
| dc.contributor.author |
Salloum, Tamara |
|
| dc.contributor.author |
Eisen, Jonathan E. |
|
| dc.contributor.author |
Jospin, Guillaume |
|
| dc.contributor.author |
Farra, Anna |
|
| dc.contributor.author |
Mokhbat, Jacques E. |
|
| dc.contributor.author |
Coil, David A. |
|
| dc.date.accessioned |
2018-06-25T10:34:43Z |
|
| dc.date.available |
2018-06-25T10:34:43Z |
|
| dc.date.copyright |
2017 |
en_US |
| dc.date.issued |
2018-06-25 |
|
| dc.identifier.issn |
1746-0921 |
en_US |
| dc.identifier.uri |
http://hdl.handle.net/10725/8092 |
|
| dc.description.abstract |
Aim: Extended-spectrum β-lactamase-producing (ESBL) Escherichia coli are a public threat worldwide. This study aimed at analyzing the genomic and functional attributes of nine ESBLs taken from rectal swabs. Materials & methods: Samples were isolated from patients admitted for gastrointestinal and urological procedures at the University Medical Center-Rizk Hospital (UMCRH) in Lebanon. Illumina paired-end libraries were prepared and sequenced. Results: The isolates were distributed into five lineages: ST131, ST648, ST405, ST73 and ST38, and harbored blaOXA-1, blaTEM-1B, blaTEM-1C and aac(6′)Ib-cr. ST131 isolates were carriers of stx2 converting I phage. Conclusion: This is the first comprehensive genomic analysis performed on ESBLs in Lebanon. |
en_US |
| dc.language.iso |
en |
en_US |
| dc.title |
Genomic attributes of extended-spectrum β-lactamase-producing Escherichia coli isolated from patients in Lebanon |
en_US |
| dc.type |
Article |
en_US |
| dc.description.version |
Published |
en_US |
| dc.author.school |
SAS |
en_US |
| dc.author.idnumber |
199736770 |
en_US |
| dc.author.idnumber |
200804713 |
en_US |
| dc.author.department |
Natural Sciences |
en_US |
| dc.description.embargo |
N/A |
en_US |
| dc.relation.journal |
Future microbiology |
en_US |
| dc.journal.volume |
12 |
en_US |
| dc.journal.issue |
3 |
en_US |
| dc.article.pages |
213-226 |
en_US |
| dc.keywords |
ESBL |
en_US |
| dc.keywords |
Escherichia coli |
en_US |
| dc.keywords |
Genomic epidemiology |
en_US |
| dc.keywords |
Lebanon |
en_US |
| dc.identifier.doi |
https://doi.org/10.2217/fmb-2017-0171 |
en_US |
| dc.identifier.ctation |
Tokajian, S., Salloum, T., Eisen, J. A., Jospin, G., Farra, A., Mokhbat, J. E., & Coil, D. A. (2017). Genomic attributes of extended-spectrum β-lactamase-producing Escherichia coli isolated from patients in Lebanon. Future microbiology, 12(3), 213-226. |
en_US |
| dc.author.email |
stokajian@lau.edu.lb |
en_US |
| dc.author.email |
anna.farra@lau.edu.lb |
en_US |
| dc.identifier.tou |
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php |
en_US |
| dc.identifier.url |
https://www.futuremedicine.com/doi/abs/10.2217/fmb-2017-0171 |
en_US |
| dc.author.affiliation |
Lebanese American University |
en_US |