Evolutionary algorithm for protein structure prediction

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dc.contributor.author Mansour, Nashat
dc.contributor.author Kanj, Fatima
dc.contributor.author Khachfe, Hassan
dc.date.accessioned 2018-05-17T12:01:24Z
dc.date.available 2018-05-17T12:01:24Z
dc.date.copyright 2010 en_US
dc.date.issued 2018-05-17
dc.identifier.isbn 978-1-4244-5961-2 en_US
dc.identifier.uri http://hdl.handle.net/10725/7855
dc.description.abstract A protein is characterized by its 3D structure, which defines its biological function. The protein structure prediction problem has real-world significance where several diseases are associated with the wrong folding of proteins. Predicting protein structures is computationally intractable. In this paper, we present an improved genetic algorithm (GA) for predicting 3D structures of proteins based on the hydrophobic polar model. We evaluate our proposed GA on a number of protein sequences. The generated protein structures demonstrate improvement over previously published results. en_US
dc.language.iso en en_US
dc.publisher IEEE Xplore en_US
dc.title Evolutionary algorithm for protein structure prediction en_US
dc.type Conference Paper / Proceeding en_US
dc.author.school SAS en_US
dc.author.idnumber 198629170 en_US
dc.author.department Computer Science and Mathematics en_US
dc.description.embargo N/A en_US
dc.keywords Protein structure prediction en_US
dc.keywords ab initio approach en_US
dc.keywords Evolutionary algorithm en_US
dc.keywords Genetic algorithms en_US
dc.keywords HP model en_US
dc.identifier.doi http://dx.doi.org/10.1109/ICNC.2010.5584796 en_US
dc.identifier.ctation Mansour, N., Kanj, F., & Khachfe, H. (2010, August). Evolutionary algorithm for protein structure prediction. In Natural Computation (ICNC), 2010 Sixth International Conference on (Vol. 8, pp. 3974-3977). IEEE. en_US
dc.author.email nmansour@lau.edu.lb en_US
dc.conference.date 10-12 Aug. 2010 en_US
dc.conference.pages 3974-3977 en_US
dc.conference.place Yantai, China en_US
dc.conference.title 2010 Sixth International Conference on Natural Computation (ICNC) en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url https://ieeexplore.ieee.org/abstract/document/5584796/ en_US
dc.orcid.id https://orcid.org/0000-0002-3603-8284 en_US
dc.author.affiliation Lebanese American University en_US

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