Transcatheter aortic valve implantation

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dc.contributor.author Hariri, Essa H.
dc.contributor.author Hachem, Ahmad A.
dc.contributor.author Chamoun, Nibal R.
dc.contributor.author Haddad, Elie K.
dc.contributor.author Tamer, Diana F.
dc.contributor.author Lteif, Christelle M.
dc.contributor.author Naja, Ahmad S.
dc.contributor.author Sarkis, George A.
dc.contributor.author Ghanem, Georges Y.
dc.date.accessioned 2017-12-19T08:24:09Z
dc.date.available 2017-12-19T08:24:09Z
dc.date.copyright 2017 en_US
dc.date.issued 2017-12-19
dc.identifier.issn 0023-9852 en_US
dc.identifier.uri http://hdl.handle.net/10725/6833
dc.description.abstract Background : Transcatheter aortic valve implantation(TAVI) has recently emerged as a therapeuticalternative for high-risk surgical patients with severe symptomaticaortic valve stenosis and has been shown to improveclinical outcomes and reduce all-cause mortality in thePARTNER Trial. However, there is still no published data onsimilar outcomes in the Lebanon. Objectives : The aim ofthe study is to evaluate the immediate and short-term resultsof transfemoral (TF) and transaortic (TAo) TAVI done in Lebanonwith 6 months follow-up. Methods: From July 2012 tillMarch 2015, 10 consecutive high-risk and intermediate riskpatients with severe symptomatic AS underwent TAVI usingEdwards SAPIEN valve. The mean age was 79.4 ± 6.9 years,logistic EuroSCORE 12.56 ± 11.78 and mean STS 5.71 ±2.44. Patients were equally distributed among genders (50%).The mean ejection fraction (EF) was 50.0 ± 14.9% and meanAV area 0.61 ± 0.1 cm2; mean aortic valve gradient (mAVG)45.6 ± 20.2 mmHg, and AV annulus size 21.8 ± 1.8 mm.Results: TF approach was performed in 9 patients (90%) andTAo in 1 patient (10%). All valves (17 size 26 mm and 25 size23 mm) were implanted successfully. The overall 6-monthsurvival was 80%. Grade I paravalvular aortic regurgitation(AR) was present in 60% of the patients; grade II in 10%while none of the patients developed AR with grade III or VI.The post-procedural mean aortic valve gradient (mAVG) was9.77 ± 3.31 mmHg; EF was 52.5 ± 11.9% and immediatepostoperative complications included only one case of newonsetarrhythmia (AV Block). After 6 months, one patient diedof cardiac arrest following a massive pulmonary embolismwhile another patient died from a fatal stroke following infectiveendocarditis affecting the valve prosthesis. Conclusion:TAVI is a feasible technique for intermediate/high risk AS withhigh success rate and acceptable complications. en_US
dc.language.iso en en_US
dc.title Transcatheter aortic valve implantation en_US
dc.type Article en_US
dc.description.version Published en_US
dc.title.subtitle acute and 6-month outcomes of the first Lebanese experience and aliterature review en_US
dc.author.school SOP en_US
dc.author.school SOM
dc.author.idnumber 200201071 en_US
dc.author.idnumber 201000163 en_US
dc.author.department Pharmacy Practice en_US
dc.description.embargo N/A en_US
dc.relation.journal Lebanese Medical Journal en_US
dc.journal.volume 65 en_US
dc.journal.issue 1 en_US
dc.article.pages 7-14 en_US
dc.identifier.doi http://dx.doi.org/10.12816/0035664 en_US
dc.identifier.ctation Hariri, E. H., Hachem, A. A., Chamoun, N. R., Haddad, E. K., Tamer, D. F., Lteif, C. M., ... & Ghanem, G.Y. (2017). Transcatheter Aortic Valve Implantation: Acute and 6-Month Outcomes of the First Lebanese Experience and Aliterature Review. Lebanese Medical Journal, 65(1), 7-14. en_US
dc.author.email nibal.chamoun@lau.edu.lb en_US
dc.author.email george.ghanem@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url http://platform.almanhal.com/Details/Article/99967 en_US
dc.orcid.id https://orcid.org/0000-0002-0987-296X en_US
dc.orcid.id https://orcid.org/0000-0002-0850-0689
dc.author.affiliation Lebanese American University en_US

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