Potentially inappropriate home medications among older patients with cardiovascular disease admitted to a cardiology service in USA

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dc.contributor.author Sheikh-Taha, Marwan
dc.contributor.author Dimassi, Hani
dc.date.accessioned 2017-12-13T10:13:11Z
dc.date.available 2017-12-13T10:13:11Z
dc.date.copyright 2017 en_US
dc.date.issued 2017-12-13
dc.identifier.issn 1471-2261 en_US
dc.identifier.uri http://hdl.handle.net/10725/6779
dc.description.abstract Background: The use of potentially inappropriate medications (PIMs) may pose more risks than benefits to patients and is a major factor contributing to the likelihood of serious adverse drug reactions and negative health outcomes among older patients. Methods: A retrospective chart review was conducted in a tertiary care center in USA where home medications of the older patients were reviewed and analyzed upon hospital admission over three months, from March till May 2016. Inclusion criteria were age of 65 years and above, history of cardiovascular disease, and admission to the cardiology service. The aim of our study was to determine the frequency and factors associated with PIMs, by applying the updated Beers 2015 criteria. Results: A total of 404 patients were included in the study and were taking a total of 4669 medications at home, an average of 11.6 ± 4.5 medications per patient. The proportion of PIMS was 20% of all medications reported, with an average of 2.4 PIM per patient, and 87.4% of patients were receiving at least one PIM. Significant association was found between use of PIMs and number of home medications, female gender, and number and types of comorbidities. Comorbidities associated with more PIMs were heart failure, atrial fibrillation/flutter, history of falls/fractures, cerebrovascular accident, and depression. The most commonly prescribed PIMs were: drugs that may exacerbate or cause syndrome of inappropriate antidiuretic hormone secretion or hyponatremia (29.7%), scheduled use of proton pump inhibitors (PPIs) > 8 weeks in non-high-risk patients (11.3%), and benzodiazepines (8.1%). Conclusions: A high prevalence of PIMs in older patients with cardiovascular disease was observed. Provider education and detailed assessment of medication lists upon hospital admission by multidisciplinary teams can help in preventing the use of PIMs. en_US
dc.language.iso en en_US
dc.title Potentially inappropriate home medications among older patients with cardiovascular disease admitted to a cardiology service in USA en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOP en_US
dc.author.idnumber 199410150 en_US
dc.author.idnumber 200603781 en_US
dc.author.department Pharmacy Practice Department en_US
dc.description.embargo N/A en_US
dc.relation.journal BMC Cardiovascular Disorders en_US
dc.journal.volume 17 en_US
dc.journal.issue 189 en_US
dc.article.pages 1-6
dc.keywords Beer’s criteria en_US
dc.keywords Cardiovascular disease en_US
dc.keywords Geriatrics en_US
dc.keywords Potentially inappropriate medications en_US
dc.identifier.doi http://dx.doi.org/10.1186/s12872-017-0623-1 en_US
dc.identifier.ctation Sheikh-Taha, M., & Dimassi, H. (2017). Potentially inappropriate home medications among older patients with cardiovascular disease admitted to a cardiology service in USA. BMC cardiovascular disorders, 17(1), 189. en_US
dc.author.email marwan.taha@lau.edu.lb en_US
dc.author.email hani.dimassi@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url https://bmccardiovascdisord.biomedcentral.com/articles/10.1186/s12872-017-0623-1 en_US
dc.orcid.id https://orcid.org/0000-0002-8037-1201 en_US
dc.orcid.id https://orcid.org/0000-0003-1827-2453 en_US
dc.author.affiliation Lebanese American University en_US

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