| dc.contributor.editor |
Cohen, I.R. |
|
| dc.contributor.editor |
Lambris, J.D. |
|
| dc.contributor.editor |
Paoletti, R. |
|
| dc.contributor.editor |
Rezaei, N. |
|
| dc.date.accessioned |
2017-11-16T12:34:08Z |
|
| dc.date.available |
2017-11-16T12:34:08Z |
|
| dc.date.copyright |
2012 |
en_US |
| dc.date.issued |
2017-11-16 |
|
| dc.identifier.isbn |
9789400728882 |
en_US |
| dc.identifier.uri |
http://hdl.handle.net/10725/6625 |
|
| dc.description.abstract |
Cyclic variations in calcium (Ca2+) concentrations, through a process called excitation-contraction coupling, allow regulation of vascular smooth muscle cells contractility and thus modulation of vascular tone and blood pressure. As a second messenger, Ca2+ also activates signaling cascades leading to transcription factors activation in a process called excitation-transcription coupling. Furthermore, recent evidences indicate an interaction between post-transcriptional regulation by microRNAs (miRNAs) and Ca2+ signaling. All these actors, which are frequently altered in vascular diseases, will be reviewed here. |
en_US |
| dc.language.iso |
en |
en_US |
| dc.publisher |
Springer |
en_US |
| dc.publisher |
Springer Netherland |
en_US |
| dc.relation.ispartofseries |
Advances in Experimental Medicine and Biology, v. 740 |
en_US |
| dc.subject |
Medicine |
en_US |
| dc.subject |
Neurosciences |
en_US |
| dc.subject |
Cell receptors |
en_US |
| dc.title |
Calcium signaling |
en_US |
| dc.type |
Book / Chapter of a Book |
en_US |
| dc.author.school |
SOM |
en_US |
| dc.author.idnumber |
201402416 |
en_US |
| dc.author.department |
N/A |
en_US |
| dc.publication.place |
Dordrecht |
en_US |
| dc.keywords |
Calcium signaling |
en_US |
| dc.keywords |
Excitation-contraction |
en_US |
| dc.keywords |
Excitation-transcription |
en_US |
| dc.keywords |
microRNA |
en_US |
| dc.keywords |
Physiopathology |
en_US |
| dc.keywords |
Vascular smooth muscle |
en_US |
| dc.description.bibliographiccitations |
Includes bibliographical references |
en_US |
| dc.identifier.doi |
https://doi.org/10.1007/978-94-007-2888-2_35 |
en_US |
| dc.identifier.ctation |
Marchand, A., Abi-Gerges, A., Saliba, Y., Merlet, E., & Lompré, A. M. (2012). Calcium signaling in vascular smooth muscle cells: from physiology to pathology. In Calcium Signaling (pp. 795-810). Springer Netherlands. |
en_US |
| dc.chapter.author |
Marchand, Alexandre |
|
| dc.chapter.author |
Abi-Gerges, Aniella |
|
| dc.chapter.author |
Saliba, Youakim |
|
| dc.chapter.author |
Merlet, Elise |
|
| dc.chapter.author |
Lompré, Anne-Marie |
|
| dc.author.email |
aniella.abigerges@lau.edu.lb |
en_US |
| dc.chapter.pages |
795-810 |
en_US |
| dc.chapter.title |
Calcium signaling in vascular smooth muscle cells: from physiology to pathology |
en_US |
| dc.identifier.tou |
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php |
en_US |
| dc.identifier.url |
https://link.springer.com/chapter/10.1007/978-94-007-2888-2_35 |
en_US |
| dc.orcid.id |
https://orcid.org/0000-0001-9974-4023 |
en_US |
| dc.author.affiliation |
Lebanese American University |
en_US |