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Syringolymphoid hyperplasia and follicular mucinosis in a patient with cutaneous T-cell lymphoma

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dc.contributor.author Tannous, Zeina
dc.contributor.author Baldassano, Marisa F.
dc.contributor.author Li, Vincent W.
dc.contributor.author Kvedar, Joseph
dc.contributor.author Duncan, Lyn M.
dc.date.accessioned 2017-11-08T10:29:14Z
dc.date.available 2017-11-08T10:29:14Z
dc.date.copyright 1999 en_US
dc.identifier.issn 2352-5126 en_US
dc.identifier.uri http://hdl.handle.net/10725/6554
dc.description.abstract Syringolymphoid hyperplasia with alopecia is an uncommon chronic dermatosis of which 9 cases have been reported, with or without follicular mucinosis or cutaneous T-cell lymphoma. We report a patient with cutaneous T-cell lymphoma and syringolymphoid hyperplasia and follicular mucinosis and review the previously reported cases. All reported cases with syringolymphoid hyperplasia were men (10 of 10), with the clinical findings of alopecia (9 of 10) and anhidrosis (3 of 10). Only 3 of 10 cases had associated follicular mucinosis. Of the 7 cases investigated, 6 were found to hve cutaneous T-cell lymphoma. Three patients were not investigated for cutaneous T-cell lymphoma. Although syringolymphoid hyperplasia can be idiopathic, it can also reflect a syringotropic cutaneous T-cell lymphoma. Careful follow-up with a biopsy of persistent lesions is recommended to evaluate for the presence of lymphoma. (J Am Acad Dermatol 1999;41:303-8.) Syringolymphoid hyperplasia (SLH) with alopecia is an uncommon chronic dermatosis first described by Sarkany et al in 1969.1 SLH is characterized histologically by hyperplasia of eccrine ducts and glands that are infiltrated and surrounded by a dense lymphocytic infiltrate. Nine patients with SLH have been reported with or without follicular mucinosis or cutaneous T-cell lymphoma (CTCL). We report a patient with CTCL and associated SLH and follicular mucinosis. en_US
dc.language.iso en en_US
dc.title Syringolymphoid hyperplasia and follicular mucinosis in a patient with cutaneous T-cell lymphoma en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOM en_US
dc.author.idnumber 201100706 en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Journal of the American Academy of Dermatology en_US
dc.journal.volume 41 en_US
dc.journal.issue 2, supplement en_US
dc.article.pages 303-308 en_US
dc.identifier.doi https://doi.org/10.1016/S0190-9622(99)70370-1 en_US
dc.identifier.ctation Tannous, Z., Baldassano, M. F., Li, V. W., Kvedar, J., & Duncan, L. M. (1999). Syringolymphoid hyperplasia and follicular mucinosis in a patient with cutaneous T-cell lymphoma. Journal of the American Academy of Dermatology, 41(2), 303-308. en_US
dc.author.email zeina.tannous@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url http://www.sciencedirect.com/science/article/pii/S0190962299703701 en_US
dc.author.affiliation Lebanese American University en_US


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