Confirmation of iminoacridan structure of singly protonated 9-aminoacridine

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dc.contributor.author Capomacchia, Anthony C.
dc.contributor.author Schulman, Stephen G.
dc.date.accessioned 2017-10-18T06:03:54Z
dc.date.available 2017-10-18T06:03:54Z
dc.date.copyright 1975 en_US
dc.date.issued 2017-10-18
dc.identifier.issn 1520-6017 en_US
dc.identifier.uri http://hdl.handle.net/10725/6338
dc.description.abstract The occurrence of the second absorption band of singly protonated 9-aminoacridine, which arises from an acridinium ring-localized transition, at anomalously short wavelength indicates the disruption of the aromaticity of the central ring of the singly charged cation. The shifting of the two longest wavelength absorption bands and the fluorescence band of 10-methyl-9-aminoacridine monocation, a model of singly protonated 9-aminoacridine which is constrained to dissociate from the exocyclic nitrogen atom, to shorter wavelengths, upon dissociation, indicates the imine-like nature of the 10-methyl derivative. These observations support the conclusion that the predominant site of positive charge in singly protonated 9-aminoacridine is the exocyclic nitrogen atom, even though the heterocyclic nitrogen atom is the site of protonation of the neutral molecule. en_US
dc.language.iso en en_US
dc.title Confirmation of iminoacridan structure of singly protonated 9-aminoacridine en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOP en_US
dc.author.idnumber 201408778 en_US
dc.author.department Pharmaceutical Sciences Department en_US
dc.description.embargo N/A en_US
dc.relation.journal Journal of Pharmaceutical Sciences en_US
dc.journal.volume 64 en_US
dc.journal.issue 7 en_US
dc.article.pages 1256-1257 en_US
dc.identifier.doi http://dx.doi.org/10.1002/jps.2600640734 en_US
dc.identifier.ctation Capomacchia, A. C., & Schulman, S. G. (1975). Confirmation of iminoacridan structure of singly protonated 9‐aminoacridine. Journal of pharmaceutical sciences, 64(7), 1256-1257. en_US
dc.author.email anthony.capomacchia@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url http://onlinelibrary.wiley.com/doi/10.1002/jps.2600640734/full en_US
dc.author.affiliation Lebanese American University en_US

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