Protein structure prediction in the 3D HP model

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dc.contributor.author Abu-Khzam, Faisal
dc.contributor.author Mansour, Nashat
dc.contributor.author Kanj, Fatima
dc.contributor.author Khachfe, Hassan
dc.date.accessioned 2017-04-11T11:59:36Z
dc.date.available 2017-04-11T11:59:36Z
dc.date.copyright 2009 en_US
dc.identifier.isbn 9781424438068 en_US
dc.identifier.uri http://hdl.handle.net/10725/5538
dc.description.abstract Proteins are initially linear chains of amino acids that fold, under the influence of several chemical and physical factors, into their 3-dimensional structures. Due to the importance of this problem and since laboratory techniques are not always feasible, computational methods for characterizing protein structures have been proposed. In this paper, we present a Particle Swarm Optimization (PSO) based algorithm for predicting protein structures in the 3D HP model. Starting from a small set of potential solutions, our algorithm efficiently explores the search space of candidate solutions and returns 3D protein structures with minimal energy. To test our algorithm, we use two sets of benchmark sequences of different lengths. It is found that the results of the PSO algorithm are better than those of previous algorithms en_US
dc.language.iso en en_US
dc.publisher IEEE en_US
dc.title Protein structure prediction in the 3D HP model en_US
dc.type Conference Paper / Proceeding en_US
dc.author.school SAS en_US
dc.author.idnumber 200302941 en_US
dc.author.idnumber 198629170 en_US
dc.author.department Computer Science and Mathematics en_US
dc.description.embargo N/A en_US
dc.keywords 3-dimensional structures en_US
dc.keywords Candidate solution en_US
dc.keywords Hp model en_US
dc.keywords Laboratory techniques en_US
dc.keywords Linear chain en_US
dc.keywords Minimal energy en_US
dc.keywords Physical factors en_US
dc.keywords Potential solutions en_US
dc.keywords Protein structure prediction en_US
dc.keywords PSO algorithms en_US
dc.keywords Search spaces en_US
dc.identifier.doi http://dx.doi.org/10.1109/AICCSA.2009.5069408 en_US
dc.identifier.ctation Kanj, F., Mansour, N., Khachfe, H., & Abu-Khzam, F. (2009, May). Protein structure prediction in the 3D HP model. In Computer Systems and Applications, 2009. AICCSA 2009. IEEE/ACS International Conference on (pp. 732-736). IEEE. en_US
dc.author.email faisal.abukhzam@lau.edu.lb en_US
dc.author.email nmansour@lau.edu.lb en_US
dc.conference.date 10-13 May, 2009 en_US
dc.conference.pages 732-736 en_US
dc.conference.place Rabat; Morocco en_US
dc.conference.title 7th IEEE/ACS International Conference on Computer Systems and Applications, AICCSA-2009 en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url http://ieeexplore.ieee.org/document/5069408/ en_US
dc.publication.date 2009 en_US
dc.author.affiliation Lebanese American University en_US

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