Exposure rates to hepatitis C and G virus infections among HIV-infected patients

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dc.contributor.author Mokhbat, J.
dc.contributor.author Ramia, S.
dc.contributor.author Klayme, S.
dc.contributor.author Naman, R.
dc.contributor.author Sibai, A.
dc.date.accessioned 2017-02-13T12:12:04Z
dc.date.available 2017-02-13T12:12:04Z
dc.date.copyright 2004 en_US
dc.identifier.issn 0956-4624 en_US
dc.identifier.uri http://hdl.handle.net/10725/5228
dc.description.abstract The importance of sexual transmission in the epidemiology of hepatitis G virus (HGV) and hepatitis C virus (HCV) was evaluated in two groups of HIV-1-positive Lebanese patients. Members of one group (90 patients) were HIV-1-infected via sexual route and denied intravenous drug (IVD) use, while members of the other group (28 patients) became HIV-1-infected parenterally and confessed frequent IVD use. The overall prevalence of HGV infection was relatively high in both groups and with no statistically significant difference between them (28% among IVD users vs 32% among the non-IVD users) despite the fact that non-IVD users were significantly older (32.7+1.7 years) than the IVD users (24.0+1.4 years) (P50.01). Conversely, there was a clear association between IVD use and HCV infection (25% for IVD users vs 7% for non-IVD users) despite the significantly lower age of the IVD users. These results point to the efficient transmission of HGV via the sexual route, while the transmission of HCV is mainly via the parenteral route. CD4+ lymphocyte counts were known on only 82 HIV- 1-infected patients. Although the number of HGV-RNA-positive patients (three) was small compared with anti-HGV-positive patients (24), a relationship was not found between CD4+ lymphocyte counts and the presence of HGV-RNA in the HIV-1-positive patients. The role of HGV in causing significant liver disease is still under dispute en_US
dc.language.iso en en_US
dc.title Exposure rates to hepatitis C and G virus infections among HIV-infected patients en_US
dc.type Article en_US
dc.description.version Published en_US
dc.title.subtitle evidence of efficient transmission of HGV by the sexual route en_US
dc.author.school SOM en_US
dc.author.idnumber 200902719 en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal International Journal of STD & AIDS en_US
dc.journal.volume 15 en_US
dc.article.pages 463-466 en_US
dc.keywords Hepatitis G virus en_US
dc.keywords Hepatitis C virus en_US
dc.keywords Human immunodeficiency virus en_US
dc.keywords Intravenous drug users en_US
dc.keywords Sexual transmission en_US
dc.identifier.ctation Ramia, S., Mokhbat, J., Sibai, A., Klayme, S., & Naman, R. (2004). Exposure rates to hepatitis C and G virus infections among HIV-infected patients: evidence of efficient transmission of HGV by the sexual route. International journal of STD & AIDS, 15(7), 463-466. en_US
dc.author.email jacques.mokhbat@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url http://journals.sagepub.com/doi/pdf/10.1258/0956462041211180 en_US
dc.author.affiliation Lebanese American University en_US

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