Introduction of HIV-2 and multiple HIV-1 subtypes to Lebanon

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dc.contributor.author Mokhbat, Jacques E.
dc.contributor.author Pieniazek, Danuta
dc.contributor.author Baggs, James
dc.contributor.author Matar, Ghassan M.
dc.contributor.author Abdelnoor, Alexander M.
dc.contributor.author Uwaydah, Marwan
dc.contributor.author Bizri, Abdul Rahman
dc.contributor.author Ramos, Artur
dc.contributor.author Janini, Luiz M.
dc.contributor.author Tanuri, Amilcar
dc.contributor.author Fridlund, Carol
dc.contributor.author Heyndrickx, Leo
dc.contributor.author Rayfield, Mark A.
dc.contributor.author Heneine, Walid
dc.date.accessioned 2017-02-10T08:29:48Z
dc.date.available 2017-02-10T08:29:48Z
dc.date.copyright 1998 en_US
dc.date.issued 2017-02-10
dc.identifier.issn 1080-6040 en_US
dc.identifier.uri http://hdl.handle.net/10725/5203
dc.description.abstract HIV genetic variability, phylogenetic relationships, and transmission dynamics were analyzed in 26 HIV-infected patients from Lebanon. Twenty-five specimens were identified as HIV-1 and one as HIV-2 subtype B. The 25 strains were classified into six env-C2-V3 HIV-1 subtypes: B (n = 10), A (n = 11), C (n = 1), D (n = 1), G (n = 1), and unclassifiable. Potential recombinants combining parts of viral regions from different subtypes Aenv/Dpol/Agag, Genv/Apol, and the unclassifiable-subtype(env)/unclassifiable-subtype(pol)/Agag were found in three patients. Epidemiologic analysis of travel histories and behavioral risks indicated that HIV-1 and HIV-2 subtypes reflected HIV strains prevalent in countries visited by patients or their sex partners. Spread of complex HIV-subtype distribution patterns to regions where HIV is not endemic may be more common than previously thought. Blood screening for both HIV-1 and HIV-2 in Lebanon is recommended to protect the blood supply. HIV subtype data provide information for vaccine development en_US
dc.language.iso en en_US
dc.title Introduction of HIV-2 and multiple HIV-1 subtypes to Lebanon en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOM en_US
dc.author.idnumber 200902719 en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Emerging Infections Diseases en_US
dc.journal.volume 4 en_US
dc.journal.issue 4 en_US
dc.article.pages 649-656 en_US
dc.identifier.doi http://dx.doi.org/10.3201/eid0404.980418
dc.identifier.ctation Pieniazek, D., Baggs, J., Hu, D. J., Matar, G. M., Abdelnoor, A. M., Mokhbat, J. E., ... & Tanuri, A. (1998). Introduction of HIV-2 and multiple HIV-1 subtypes to Lebanon. Emerging infectious diseases, 4(4), 649. en_US
dc.author.email jacques.mokhbat@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640249/pdf/9866744.pdf en_US
dc.author.affiliation Lebanese American University en_US

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