dc.contributor.author |
Mokhbat, Jacques E. |
|
dc.contributor.author |
Pieniazek, Danuta |
|
dc.contributor.author |
Baggs, James |
|
dc.contributor.author |
Matar, Ghassan M. |
|
dc.contributor.author |
Abdelnoor, Alexander M. |
|
dc.contributor.author |
Uwaydah, Marwan |
|
dc.contributor.author |
Bizri, Abdul Rahman |
|
dc.contributor.author |
Ramos, Artur |
|
dc.contributor.author |
Janini, Luiz M. |
|
dc.contributor.author |
Tanuri, Amilcar |
|
dc.contributor.author |
Fridlund, Carol |
|
dc.contributor.author |
Heyndrickx, Leo |
|
dc.contributor.author |
Rayfield, Mark A. |
|
dc.contributor.author |
Heneine, Walid |
|
dc.date.accessioned |
2017-02-10T08:29:48Z |
|
dc.date.available |
2017-02-10T08:29:48Z |
|
dc.date.copyright |
1998 |
en_US |
dc.date.issued |
2017-02-10 |
|
dc.identifier.issn |
1080-6040 |
en_US |
dc.identifier.uri |
http://hdl.handle.net/10725/5203 |
|
dc.description.abstract |
HIV genetic variability, phylogenetic relationships, and transmission dynamics were analyzed in 26 HIV-infected patients from Lebanon. Twenty-five specimens were identified as HIV-1 and one as HIV-2 subtype B. The 25 strains were classified into six env-C2-V3 HIV-1 subtypes: B (n = 10), A (n = 11), C (n = 1), D (n = 1), G (n = 1), and unclassifiable. Potential recombinants combining parts of viral regions from different subtypes Aenv/Dpol/Agag, Genv/Apol, and the unclassifiable-subtype(env)/unclassifiable-subtype(pol)/Agag were found in three patients. Epidemiologic analysis of travel histories and behavioral risks indicated that HIV-1 and HIV-2 subtypes reflected HIV strains prevalent in countries visited by patients or their sex partners. Spread of complex HIV-subtype distribution patterns to regions where HIV is not endemic may be more common than previously thought. Blood screening for both HIV-1 and HIV-2 in Lebanon is recommended to protect the blood supply. HIV subtype data provide information for vaccine development |
en_US |
dc.language.iso |
en |
en_US |
dc.title |
Introduction of HIV-2 and multiple HIV-1 subtypes to Lebanon |
en_US |
dc.type |
Article |
en_US |
dc.description.version |
Published |
en_US |
dc.author.school |
SOM |
en_US |
dc.author.idnumber |
200902719 |
en_US |
dc.author.department |
N/A |
en_US |
dc.description.embargo |
N/A |
en_US |
dc.relation.journal |
Emerging Infections Diseases |
en_US |
dc.journal.volume |
4 |
en_US |
dc.journal.issue |
4 |
en_US |
dc.article.pages |
649-656 |
en_US |
dc.identifier.doi |
http://dx.doi.org/10.3201/eid0404.980418 |
|
dc.identifier.ctation |
Pieniazek, D., Baggs, J., Hu, D. J., Matar, G. M., Abdelnoor, A. M., Mokhbat, J. E., ... & Tanuri, A. (1998). Introduction of HIV-2 and multiple HIV-1 subtypes to Lebanon. Emerging infectious diseases, 4(4), 649. |
en_US |
dc.author.email |
jacques.mokhbat@lau.edu.lb |
en_US |
dc.identifier.tou |
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php |
en_US |
dc.identifier.url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640249/pdf/9866744.pdf |
en_US |
dc.author.affiliation |
Lebanese American University |
en_US |