Atypical choroid plexus papilloma treated with single agent bevacizumab

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dc.contributor.author Nasser, Selim M.
dc.contributor.author Kamar, Francois G.
dc.contributor.author Fairouz, Victor F.
dc.contributor.author Faddoul, Sami G.
dc.contributor.author Saikali, Ibrahim C.
dc.date.accessioned 2017-02-02T10:04:15Z
dc.date.available 2017-02-02T10:04:15Z
dc.date.copyright 2014 en_US
dc.date.issued 2017-02-02
dc.identifier.issn 2036-3605 en_US
dc.identifier.uri http://hdl.handle.net/10725/5156
dc.description.abstract Choroid plexus papillomas (CPPs) are usually not malignant and occur in less than 1% of brain tumors in patients of all ages. They represent 3% of childhood intracranial neoplasms with a predilection in younger ages. Papillomas have an indolent course and carry a good long-term outcome if gross total surgical resection is achieved. However malignant evolution may occur, with a 10-30% incidence. Chemotherapy has been used with varied degrees of success. Most series are very small, some are only limited to case reports and cannot lead to guidelines or therapeutic recommendations. We are reporting the first case of recurrent CPP treated with 5 mg/kg of bevacizumab administered once every two weeks. Complete patient evaluations with follow-up contrast-enhanced magnetic resonance imaging (MRI) scans were obtained after the initial two treatments and every 8 weeks thereafter. Only after two treatments, the MRI scans showed radiological stabilization of the tumor, and the patient achieved an excellent clinical response with significant resolution of all skin lesions. en_US
dc.language.iso en en_US
dc.title Atypical choroid plexus papilloma treated with single agent bevacizumab en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOM en_US
dc.author.idnumber 200804624 en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Rare Tumors en_US
dc.journal.volume 6 en_US
dc.journal.issue 1 en_US
dc.article.pages 33-35
dc.keywords Choroid plexus papilloma en_US
dc.keywords Malignant en_US
dc.keywords Bevacizumab en_US
dc.keywords Chemotherapy en_US
dc.keywords Antiangiogenic en_US
dc.identifier.doi http://dx.doi.org/10.4081/rt.2014.4687 en_US
dc.identifier.ctation Kamar, F. G., Kairouz, V. F., Nasser, S. M., Faddoul, S. G., & Saikali, I. C. (2014). Atypical choroid plexus papilloma treated with single agent bevacizumab. Rare tumors, 6(1), 33-35 en_US
dc.author.email selim.nasser@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url http://www.pagepress.org/journals/index.php/rt/article/view/4687 en_US
dc.author.affiliation Lebanese American University en_US

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