Carcinogenic and neurotoxic risks of acrylamide and heavy metals from potato and corn chips consumed by the Lebanese population

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dc.contributor.author Mroueh, Mohamad
dc.contributor.author Korfali, Samira
dc.contributor.author Taleb, Robin I.
dc.contributor.author Hariri, Essa
dc.contributor.author Abboud, Martine I.
dc.contributor.author Demerdjian, Sally
dc.date.accessioned 2016-10-13T06:55:06Z
dc.date.available 2016-10-13T06:55:06Z
dc.date.copyright 2015 en_US
dc.date.issued 2016-10-13
dc.identifier.issn 0889-1575 en_US
dc.identifier.uri http://hdl.handle.net/10725/4583
dc.description.abstract The present study aims to quantify acrylamide and metals in potato and corn chips and to determine their carcinogenic and neurotoxic risks. Gas chromatography mass spectrometry analysis revealed that the average acrylamide level in potato and corn chips (1756 μg/kg) was 3500-fold higher than the permissible limit for acrylamide in drinking water (0.5 μg/kg). Potato-based chips and baked chips were found to contain 23% and 18% more acrylamide than corn-based chips and fried chips, respectively. The daily consumption of acrylamide from potato and corn chips was found to be 7–40-fold higher than the risk intake for carcinogenesis set by World Health Organization (WHO) but was below the neurotoxic risk threshold. Energy dispersive X-ray fluorescence and thermal atomic absorption analysis revealed that the mean concentrations of zinc, lead and cadmium in corn chips were approximately 1.5-, 1.7- and 2.4-fold higher than the permissible limits set by Food and Agriculture Organization/WHO, respectively. However, the daily intake of these metals was lower than the oral reference dose and the upper tolerable daily intake set by the US Food and Drug Administration. The cancer risk for the Lebanese population from acrylamide exposure estimations appears to be significant, highlighting the need to conduct further epidemiological studies and ensure monitoring of acrylamide levels in food products. en_US
dc.language.iso en en_US
dc.title Carcinogenic and neurotoxic risks of acrylamide and heavy metals from potato and corn chips consumed by the Lebanese population en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOP en_US
dc.author.idnumber 199590020 en_US
dc.author.idnumber 197829160 en_US
dc.author.idnumber 200901968 en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Journal of Food Composition and Analysis en_US
dc.journal.volume 42 en_US
dc.article.pages 91-97 en_US
dc.keywords Food analysis en_US
dc.keywords Food composition en_US
dc.keywords Potato chips en_US
dc.keywords Potato crisps en_US
dc.keywords Corn chips en_US
dc.keywords Corn crisps en_US
dc.keywords Acrylamide en_US
dc.keywords Heavy metals en_US
dc.keywords Carcinogenic en_US
dc.keywords Neurotoxic en_US
dc.keywords Gas chromatography mass spectrometry en_US
dc.keywords Fluorescence en_US
dc.keywords Atomic absorption en_US
dc.keywords Food processing en_US
dc.keywords Thermal treatment and Maillard reaction en_US
dc.keywords Food safety en_US
dc.identifier.doi http://dx.doi.org/10.1016/j.jfca.2015.03.009 en_US
dc.identifier.ctation Hariri, E., Abboud, M. I., Demirdjian, S., Korfali, S., Mroueh, M., & Taleb, R. I. (2015). Carcinogenic and neurotoxic risks of acrylamide and heavy metals from potato and corn chips consumed by the Lebanese population. Journal of Food Composition and Analysis, 42, 91-97. en_US
dc.author.email mmroueh@lau.edu.lb en_US
dc.author.email skorfali@lau.edu.lb en_US
dc.author.email robin.taleb@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url http://www.sciencedirect.com/science/article/pii/S0889157515001052 en_US
dc.orcid.id https://orcid.org/0000-0002-2038-510X en_US

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