Abstract:
Background: Abdominal pain and nausea following ERCP are common, and may in part relate to bowel insufflation with air. CO2 insufflation during colonoscopy reduces post-procedural pain scores as compared with air. However, there are limited data regarding the symptomatic benefit of CO2 when used in ERCP. Aims: To compare the incidence and severity of post-ERCP pain and nausea in patients receiving CO2 vs. air for insufflation during ERCP, using a prospective trial of 100 patients. Methods: Patients presenting for ERCP were randomized to receive insufflation with either air or CO2; all other care was identical.
Citation:
Keswani, R. N., Hovis, R. M., Edmundowicz, S. A., Sadeddin, E. Z., Jonnalagadda, S. S., Azar, R. R., ... & Maple, J. T. (2008). Carbon Dioxide (CO2) Insufflation during ERCP for the Reduction of Post-procedure Pain: Preliminary Results of a Randomized, Double-blind Controlled Trial. Gastrointestinal Endoscopy, 67(5), AB107.