A Review of Commonly Prescribed Antiviral and Antiretroviral Agents

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dc.contributor.author Mansour, Hanine
dc.contributor.author Inge, Lisa Devito
dc.contributor.author Ferreira, Jason
dc.contributor.author Unger, Nathan R.
dc.date.accessioned 2016-09-29T11:50:15Z
dc.date.available 2016-09-29T11:50:15Z
dc.date.copyright 2011 en_US
dc.date.issued 2016-09-29
dc.identifier.issn 8755-1225 en_US
dc.identifier.uri http://hdl.handle.net/10725/4454
dc.description.abstract Objective: To review the pharmacologic properties of and uses for the most commonly prescribed antiviral agents. Data Sources: A MEDLINE/PubMed search (1966–September 2010) was conducted for English-language articles using the terms HIV, hepatitis, cytomegalovirus (CMV), herpes simplex virus (HSV), antiviral agents, antiretroviral agent, acyclovir, valganciclovir, valacyclovir, interferon, ribavirin, ritonavir, efavirenz, zidovudine, darunavir, lopinavir, tenofovir, raltegravir, lamivudine, atazanavir, and emtricitabine. Book chapters and recent guidelines pertaining to the pathophysiology or pharmacologic properties of antiviral agents were also reviewed. Study Selection and Data Extraction: Articles, chapters, and guidelines pertaining to the relevant pharmacologic agents were collected for review. Data Synthesis: Viral pathogens affect multiple organs, causing direct and indirect damage by activating an immune response. Unlike bacterial infections, which can be eradicated from the host system, viral infections are not curable. Antiviral treatments are prescribed to reduce morbidity and mortality. There are many antiviral and more than 20 antiretroviral agents currently approved by the FDA. These include acyclovir, valacyclovir, and famciclovir for HSV; ganciclovir, valganciclovir, foscarnet, and cidofovir for CMV; interferon and ribavirin for hepatitis; efavirenz, tenofovir, emtricitabine, atazanavir, darunavir, lopinavir, ritonavir, raltegravir, zidovudine, and lamivudine as first-line agents for HIV. Conclusions: Viral illnesses affect a large portion of the population. Given the multitude of drugs available, pharmacists and pharmacy technicians should be educated about common treatment options. Having a strong knowledge of commonly prescribed antiviral drugs allows these frontline professionals to make a significant impact on the quality of care that they provide to their patients and community. en_US
dc.language.iso en en_US
dc.title A Review of Commonly Prescribed Antiviral and Antiretroviral Agents en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOP en_US
dc.author.idnumber 201205628 en_US
dc.author.department Pharmacy Practice en_US
dc.description.embargo N/A en_US
dc.relation.journal Journal of Pharmacy Technology en_US
dc.journal.volume 27 en_US
dc.journal.issue 3 en_US
dc.article.pages 99-110 en_US
dc.identifier.doi http://dx.doi.org/10.1177/875512251102700302 en_US
dc.identifier.ctation Mansour, H., Inge, L. D., Ferreira, J., & Unger, N. R. (2011). A Review of Commonly Prescribed Antiviral and Antiretroviral Agents. Journal of Pharmacy Technology, 27(3), 99-110. en_US
dc.author.email hanine.mansour@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url http://pmt.sagepub.com/content/27/3/99.short en_US
dc.orcid.id https://orcid.org/0000-0001-6383-0288

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