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Hepatoprotective activity of Centaurium erythraea on acetaminophen-induced hepatotoxicity in rats

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dc.contributor.author Mroueh, Mohamad
dc.contributor.author Saab, Yolande
dc.contributor.author Rizkallah, Raed
dc.date.accessioned 2016-09-26T08:52:22Z
dc.date.available 2016-09-26T08:52:22Z
dc.date.copyright 2004 en_US
dc.date.issued 2016-09-26
dc.identifier.issn 0951-418X en_US
dc.identifier.uri http://hdl.handle.net/10725/4383
dc.description.abstract The methanol extract of the leaves of Centaurium erythraea L. (Gentianaceae) was evaluated for hepatoprotective activity against acetaminophen-induced liver toxicity in rats. An oral dose of 300 mg/kg/day for 6 days or a single dose of 900 mg/kg for 1 day exhibited a significant protective effect by lowering serum glutamate oxaloacetate transaminase (SGOT), glutamate pyruvate transaminase (SGPT) and lactate dehydrogenase (LDH). The activity of the extract was supported by histopathological examination of liver sections. Copyright © 2004 John Wiley & Sons, Ltd. en_US
dc.language.iso en en_US
dc.title Hepatoprotective activity of Centaurium erythraea on acetaminophen-induced hepatotoxicity in rats en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOP en_US
dc.author.idnumber 199590020 en_US
dc.author.idnumber 199110360
dc.author.department Pharmaceutical Sciences en_US
dc.description.embargo N/A en_US
dc.relation.journal Phytotherapy Research en_US
dc.journal.volume 18 en_US
dc.journal.issue 5 en_US
dc.article.pages 431-433 en_US
dc.identifier.doi http://dx.doi.org/10.1002/ptr.1498 en_US
dc.identifier.ctation Mroueh, M., Saab, Y., & Rizkallah, R. (2004). Hepatoprotective activity of Centaurium erythraea on acetaminophen‐induced hepatotoxicity in rats. Phytotherapy Research, 18(5), 431-433. en_US
dc.author.email mmroueh@lau.edu.lb en_US
dc.author.email ysaab@lau.edu.lb
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url http://onlinelibrary.wiley.com/doi/10.1002/ptr.1498/abstract en_US
dc.orcid.id https://orcid.org/0000-0003-1572-7133 en_US
dc.orcid.id https://orcid.org/0000-0002-6432-582X en_US


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