Sensitivity of endoscopic ultrasound, multidetector computed tomography, and magnetic resonance cholangiopancreatography in the diagnosis of pancreas divisum

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dc.contributor.author Azar, Riad R.
dc.contributor.author Kushnir, Vladimir M.
dc.contributor.author Wani, Sachin B.
dc.contributor.author Fowler, Kathryn
dc.contributor.author Menias, Christine
dc.contributor.author Varma, Rakesh
dc.contributor.author Narra, Vamsi
dc.contributor.author Hovis, Christine
dc.contributor.author Murad, Faris M.
dc.date.accessioned 2016-09-21T09:56:41Z
dc.date.available 2016-09-21T09:56:41Z
dc.date.copyright 2013 en_US
dc.identifier.issn 0885-3177 en_US
dc.identifier.uri http://hdl.handle.net/10725/4341
dc.description.abstract Objectives: There are limited data comparing imaging modalities in the diagnosis of pancreas divisum. We aimed to: (1) evaluate the sensitivity of endoscopic ultrasound (EUS), magnetic resonance cholangiopancreatography (MRCP), and multidetector computed tomography (MDCT) for pancreas divisum; and (2) assess interobserver agreement (IOA) among expert radiologists for detecting pancreas divisum on MDCT and MRCP. Methods: For this retrospective cohort study, we identified 45 consecutive patients with pancreaticobiliary symptoms and pancreas divisum established by endoscopic retrograde pancreatography who underwent EUS and cross-sectional imaging. The control group was composed of patients without pancreas divisum who underwent endoscopic retrograde pancreatography and cross-sectional imaging. Results: The sensitivity of EUS for pancreas divisum was 86.7%, significantly higher than the sensitivity reported in the medical records for MDCT (15.5%) or MRCP (60%) (P < 0.001 for each). On review by expert radiologists, the sensitivity of MDCT increased to 83.3% in cases where the pancreatic duct was visualized, with fair IOA ([kappa] = 0.34). Expert review of MRCPs did not identify any additional cases of pancreas divisum; IOA was moderate ([kappa] = 0.43). Conclusions: Endoscopic ultrasound is a sensitive test for diagnosing pancreas divisum and is superior to MDCT and MRCP. Review of MDCT studies by expert radiologists substantially raises its sensitivity for pancreas divisum. en_US
dc.language.iso en en_US
dc.title Sensitivity of endoscopic ultrasound, multidetector computed tomography, and magnetic resonance cholangiopancreatography in the diagnosis of pancreas divisum en_US
dc.type Article en_US
dc.description.version Published en_US
dc.title.subtitle a tertiary center experience en_US
dc.author.school SOM en_US
dc.author.idnumber 200902767 en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Pancreas en_US
dc.journal.volume 42 en_US
dc.journal.issue 3 en_US
dc.article.pages 436-441 en_US
dc.keywords Pancreas divisum en_US
dc.keywords Pancreatitis en_US
dc.keywords Endoscopic ultrasound en_US
dc.keywords Magnetic resonance cholangiopancreatography en_US
dc.keywords Endoscopic retrograde cholangiopancreatography en_US
dc.keywords Computed tomography en_US
dc.identifier.doi http://dx.doi.org/10.1097/MPA.0b013e31826c711a en_US
dc.identifier.ctation Kushnir, V. M., Wani, S. B., Fowler, K., Menias, C., Varma, R., Narra, V., ... & Early, D. S. (2013). Sensitivity of Endoscopic Ultrasound, Multidetector Computed Tomography, and Magnetic Resonance Cholangiopancreatography in the Diagnosis of Pancreas Divisum: A Tertiary Center Experience. Pancreas, 42(3), 436-441. en_US
dc.author.email riad.azar@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US

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