Abstract:
In order to develop a biodegradable pin for diaphyseal femoral fracture fixation, polylactide acid (PLA) pins were implanted in the femoral bone of rats. A distal diaphyseal fracture was performed. Union and tissue reaction to PLA pins versus stainless steel pins was studied after 15 days, and 1, 2 and 6 months of implantation. PLA and stainless steel pins induced the same union and a similar tissue reaction during the 6-month period. Biocompatibility of material was satisfactory.
Citation:
Griffet, J., Accorsi, E., Chevallier, A., El Hayek, T., Odin, G., & Meouchy, W. (2002). Polylactide acid pins versus stainless steel pins in the treatment of diaphyseal fracture: Experimental study in rats. European Journal of Orthopaedic Surgery & Traumatology, 12(3), 144-151.