Absence of Congenital Prethrombotic Disorders in Children With Legg-Perthes Disease

LAUR Repository

Show simple item record

dc.contributor.author El Hayek, Toni
dc.contributor.author Sirvent, Nicolas
dc.contributor.author Fisher, Florence
dc.contributor.author Appert, Annie
dc.contributor.author Giudicelli, Henri
dc.contributor.author Griffet, Jacques
dc.date.accessioned 2016-09-20T12:21:12Z
dc.date.available 2016-09-20T12:21:12Z
dc.date.copyright 2000 en_US
dc.date.issued 2016-09-20
dc.identifier.issn 1060-152X en_US
dc.identifier.uri http://hdl.handle.net/10725/4325
dc.description.abstract Resistance to activated protein C (RPCA) and other congenital prethrombotic disorders have been recently reported to be strongly associated with Legg-Perthes disease. RPCA and deficiencies of protein C. protein S. and antithrombin III were sought in 22 children with Legg-Perthes disease. Detection of the factor V Leiden mutation was found in children with RPCA. Twenty-two healthy children paired by age and sex served as controls. The prevalence of congenital prethrombotic disorders was not found to differ significantly among patients with Legg-Perthes disease and among control subjects. Only one patient had RPCA; this patient was heterozygous for the factor V Leiden mutation. Twenty patients and all the control subjects had entirely normal coagulation results. The authors conclude that unless more data become available, RPCA and deficiencies of protein C, protein S, and antithrombin III should not be considered associated with Legg-Perthes disease. en_US
dc.language.iso en en_US
dc.title Absence of Congenital Prethrombotic Disorders in Children With Legg-Perthes Disease en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOM en_US
dc.author.idnumber 201205678 en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Journal of Pediatric Orthopaedics B en_US
dc.journal.volume 9 en_US
dc.journal.issue 1 en_US
dc.article.pages 24-27 en_US
dc.identifier.ctation Sirvent, N., Fisher, F., el Hayek, T., Appert, A., Giudicelli, H., & Griffet, J. (2000). Absence of congenital prethrombotic disorders in children with Legg-Perthes disease. Journal of Pediatric Orthopaedics B, 9(1), 24-27. en_US
dc.author.email toni.hayek@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url https://oce.ovid.com/article/01202412-200001000-00005?sequence=0&clickthrough=y en_US

Files in this item

Files Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record

Search LAUR

Advanced Search


My Account