YhbO Protects Cells against Multiple Stresses

Abdallah, Jad; Caldas, Teresa; Kthiri, Fatoum; Kern, Renee; Richarme, Gilbert

YhbO Protects Cells against Multiple Stresses

Abdallah, Jad; Caldas, Teresa; Kthiri, Fatoum; Kern, Renee; Richarme, Gilbert

URI: http://hdl.handle.net/10725/4163

URL: http://jb.asm.org/content/189/24/9140.short

DOI: http://dx.doi.org/10.1128/JB.01208-07

Date: 2016-07-19

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Abstract:

YhbO is a member of the DJ-1/ThiJ/Pfp1 superfamily, which includes chaperones, peptidases, and the Parkinson's disease protein DJ-1. A yhbO-disrupted mutant of Escherichia coli is highly sensitive to oxidative, thermal, UV, and pH stresses, and the putative nucleophilic cysteine C104 of YhbO is required for stress resistance. These results suggest that YhbO affects a central process in stress management.

Citation:

Abdallah, J., Caldas, T., Kthiri, F., Kern, R., & Richarme, G. (2007). YhbO protects cells against multiple stresses. Journal of bacteriology, 189(24), 9140-9144.