Pancreatitis following Olanzapine therapy

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dc.contributor.author Azar, Riad
dc.contributor.author Kerr, T. A.
dc.contributor.author Jonnalagadda, Sreenivasa
dc.date.accessioned 2016-06-22T09:18:52Z
dc.date.available 2016-06-22T09:18:52Z
dc.date.copyright 2007 en_US
dc.date.issued 2016-06-22
dc.identifier.issn 1662-0631 en_US
dc.identifier.uri http://hdl.handle.net/10725/4126
dc.description.abstract Context: Atypical antipsychotic agents (clozapine, olanzapine) have been linked to metabolic effects and acute pancreatitis. Case Report: We reviewed the inpatient and outpatient records of three patients who developed acute pancreatitis while being treated with olanzapine. The mean age of the patients was 37.7 years (range 18–54 years, 2 female, 1 male). No alternative cause of acute pancreatitis was found in two of the three patients. In the remaining patient, olanzapine may have contributed to acute pancreatitis in the setting of hypertriglyceridemia. Olanzapine was discontinued in all instances. Over a mean followup of 14 months, one patient has had a relapsing course, but the remaining two patients have been symptom free without recurrence of acute pancreatitis. Conclusions: Our case series adds further support to the potential link between olanzapine use and acute pancreatitis. Close monitoring of metabolic parameters is suggested in patients treated with olanzapine. Alternative antipsychotic agents should be considered in patients at high risk for pancreatitis. en_US
dc.language.iso en en_US
dc.title Pancreatitis following Olanzapine therapy en_US
dc.type Article en_US
dc.description.version Published en_US
dc.title.subtitle a report of three cases en_US
dc.author.school SOM en_US
dc.author.idnumber 200902767 en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Case Reports in Gastroenterology en_US
dc.journal.volume 1 en_US
dc.journal.issue 1 en_US
dc.article.pages 15-20 en_US
dc.keywords Pancreatitis en_US
dc.keywords Atypical antipsychotic en_US
dc.keywords Olanzapine en_US
dc.keywords Drug induced pancreatitis en_US
dc.identifier.doi http://dx.doi.org/10.1159/000104222 en_US
dc.identifier.ctation Kerr, T. A., Jonnalagadda, S., Prakash, C., & Azar, R. (2007). Pancreatitis following olanzapine Therapy: a report of three cases. Case reports in gastroenterology, 1(1), 15-20. en_US
dc.author.email riad.azar@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url http://www.karger.com/Article/Abstract/104222 en_US

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