Stenting for malignant colonic obstruction

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dc.contributor.author Azar, Riad
dc.contributor.author Keswani, Rajesh N.
dc.contributor.author Edmundowicz, Steven A.
dc.contributor.author Zhang, Qin
dc.contributor.author Ammar, Tarek
dc.contributor.author Banerjee, Bhaskar
dc.date.accessioned 2016-06-20T09:52:49Z
dc.date.available 2016-06-20T09:52:49Z
dc.date.copyright 2009 en_US
dc.date.issued 2016-06-20
dc.identifier.issn 0016-5107 en_US
dc.identifier.uri http://hdl.handle.net/10725/4107
dc.description.abstract Background: Self-expandable metal stent placement for palliation of malignant colonic obstruction for colorectal cancer (CRC) is safe and efficacious. In contrast, outcomes of stent placement for extracolonic malignancy (ECM) are unclear. Objective: To compare the success and complication rates of colorectal stenting in patients with CRC versus those with ECM. Design: Retrospective chart review. Setting: Tertiary-care academic medical center. Patients and Interventions: Between September 2000 and December 2007, all patients with malignant colon obstruction in whom endoscopy was performed with the intention of placing a colonic metal stent. Main Outcome Measurements: Technical and clinical success rates, surgical interventions, and procedure related complications. Results: Colonic stenting was performed for CRC in 34 patients and for ECM in 15 patients. Patients with CRC were more likely to have clinical success after all endoscopic therapy (94.1%) than those with ECM (20.0%) (P ! .0001). Surgical diversion to relieve persistent obstructive symptoms was required in significantly more patients with ECM. Five patients with ECM (33.3%) had at least one complication, including 2 deaths, compared with 3 patients with CRC (8.8%) (P Z .046). Only underlying ECM was predictive of failed colon stent placement by multivariate analysis (hazard ratio 21.0, P Z .0013). A history of radiation therapy was the sole predictor of complications (hazard ratio 7.8, P Z .048). Limitations: Single institution, retrospective analysis, relatively small sample size. Conclusions: Colon stenting for large-bowel obstruction from ECM is infrequently successful and is associated with a significantly higher risk of complications in comparison with patients with CRC. en_US
dc.language.iso en en_US
dc.title Stenting for malignant colonic obstruction en_US
dc.type Article en_US
dc.description.version Published en_US
dc.title.subtitle a comparison of efficacy and complications in colonic versus extracolonic malignancy en_US
dc.author.school SOM en_US
dc.author.idnumber 200902767 en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Gastrointestinal Endoscopy en_US
dc.journal.volume 69 en_US
dc.journal.issue 3, part 2 en_US
dc.article.pages 675-680 en_US
dc.identifier.doi http://dx.doi.org/10.1016/j.gie.2008.09.009 en_US
dc.identifier.ctation Keswani, R. N., Azar, R. R., Edmundowicz, S. A., Zhang, Q., Ammar, T., Banerjee, B., ... & Jonnalagadda, S. S. (2009). Stenting for malignant colonic obstruction: a comparison of efficacy and complications in colonic versus extracolonic malignancy. Gastrointestinal endoscopy, 69(3), 675-680. en_US
dc.author.email riad.azar@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url http://www.giejournal.org/article/S0016-5107(08)02590-X/abstract en_US

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