TRP-1 expression correlates with eumelanogenesis in human pigment cells in culture

Ghanem, Georges

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dc.contributor.author	Ghanem, Georges
dc.date.accessioned	2016-06-15T07:41:50Z
dc.date.available	2016-06-15T07:41:50Z
dc.date.copyright	1993	en_US
dc.date.issued	2016-06-15
dc.identifier.issn	0014-5793	en_US
dc.identifier.uri	http://hdl.handle.net/10725/4039
dc.description.abstract	We have investigated the relationship in human cultured normal and malignant melanocytes between the accumulation of mRNAs encoding tyrosinase and tyrosinase-related protein-1 (TRP-1), the activity of tyrosinase and the presence of melanin. Tyrosinase mRNA correlates with tyrosinase activity and with the presence of pheomelanin, eumelanin or both melanin types. In contrast TRP-1 mRNA is only detectable in cells containing eumelanin, which suggests a role for TRP-1 in the eumelanin synthesis pathway.	en_US
dc.language.iso	en	en_US
dc.title	TRP-1 expression correlates with eumelanogenesis in human pigment cells in culture	en_US
dc.type	Article	en_US
dc.description.version	Published	en_US
dc.author.school	SOM	en_US
dc.author.idnumber	201000163	en_US
dc.author.department	N/A	en_US
dc.description.embargo	N/A	en_US
dc.relation.journal	FEBS letters	en_US
dc.journal.volume	327	en_US
dc.journal.issue	3	en_US
dc.article.pages	307-310	en_US
dc.identifier.doi	http://dx.doi.org/10.1016/0014-5793(93)81010-W	en_US
dc.identifier.ctation	Del Marmol, V., Ito, S., Jackson, I., Vachtenheim, J., Berr, P., Ghanem, G., ... & Huez, G. (1993). TRP‐1 expression correlates with eumelanogenesis in human pigment cells in culture. FEBS letters, 327(3), 307-310.	en_US
dc.author.email	george.ghanem@lau.edu.lb	en_US
dc.identifier.tou	http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php	en_US
dc.identifier.url	http://onlinelibrary.wiley.com/doi/10.1016/0014-5793(93)81010-W/abstract	en_US