Macroporous Polyester—Covered Stent in an Experimental Abdominal Aortic Aneurysm Model

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dc.contributor.author El-Khoury, Joe
dc.contributor.author Otal, Philippe
dc.contributor.author Amin, Chauki
dc.contributor.author Delisle, Marie-Bernadette
dc.contributor.author Cerene, Alain
dc.date.accessioned 2016-06-14T06:53:12Z
dc.date.available 2016-06-14T06:53:12Z
dc.date.copyright 2001 en_US
dc.date.issued 2016-06-14
dc.identifier.issn 1526-6028 en_US
dc.identifier.uri http://hdl.handle.net/10725/4023
dc.description.abstract Purpose: To validate a recently described animal model of abdominal aortic aneurysm (AAA) and to assess a new macroporous polyester—covered stent for endovascular AAA exclusion. Methods: Twenty adult sheep had AAAs surgically created by replacing a segment of the infrarenal aorta with an autologous jugular venous graft. Three months later, surviving animals underwent percutaneous implantation of macroporous polyester—covered nitinol stents; 3 animals with untreated AAAs served as controls. Follow-up surveillance included spiral computed tomography at 1 month and digital subtraction angiography at 3 and 6 months. Endografted animals were sacrificed at 1, 3, and 6 months after implantation; specimens from all animals were examined grossly and microscopically. Results: Seven (35%) animals died within 24 hours of causes related to the technique; 1 animal developed paraplegia and was sacrificed on day 1. Three (25%) animals died of spontaneous aneurysm rupture at <10 days, and 6 received the stent-graft at 3 months. The macroporous cover did not prevent continued perfusion of the sac early after stent-graft deployment, but all aneurysms were excluded on the 1-month CT. Conclusions: Spontaneous AAA rupture occurred earlier and was not as frequent as previously described for this model. Implantation of the covered stent was feasible, but aneurysm exclusion was not immediate. en_US
dc.language.iso en en_US
dc.title Macroporous Polyester—Covered Stent in an Experimental Abdominal Aortic Aneurysm Model en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOM en_US
dc.author.idnumber 201100951 en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Journal of Endovascular Therapy en_US
dc.journal.volume 8 en_US
dc.journal.issue 4 en_US
dc.article.pages 390-400 en_US
dc.keywords Aneurysm en_US
dc.keywords Sheep model en_US
dc.keywords Memotherm stent en_US
dc.keywords Polyester en_US
dc.keywords Aneurysm exclusion en_US
dc.identifier.doi http://dx.doi.org/10.1177/152660280100800408 en_US
dc.identifier.ctation Soula, P., d'Othée, B. J., Otal, P., Amin, C., El Khoury, J., Delisle, M. B., ... & Rousseau, H. (2001). Macroporous Polyester—Covered Stent in an Experimental Abdominal Aortic Aneurysm Model. Journal of Endovascular Therapy, 8(4), 390-400. en_US
dc.author.email joe.el-khoury@lau.edu.lb
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url http://jet.sagepub.com/content/8/4/390.short en_US

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