Multivariate epidemiologic analysis of type 2 diabetes mellitus risks in the Lebanese population

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dc.contributor.author Ghassibe-Sabbagh, Michella
dc.contributor.author Deeb, Mary
dc.contributor.author Saloum, Angelique K.
dc.contributor.author Hirbli, Kamal
dc.contributor.author Ahdab, Rechdi
dc.contributor.author Zalloua, Pierre A.
dc.contributor.author Nemr, Rita
dc.contributor.author Mouzaya, Francis
dc.contributor.author Chami, Youssef
dc.contributor.author Akle, Yasmine
dc.contributor.author Platt, Daniel E.
dc.date.accessioned 2016-06-14T05:50:44Z
dc.date.available 2016-06-14T05:50:44Z
dc.date.copyright 2014 en_US
dc.identifier.issn 1758-5996 en_US
dc.identifier.uri http://hdl.handle.net/10725/4020
dc.description.abstract Background: The burden of diabetes in Lebanon requires well-targeted interventions for screening type 2 diabetes mellitus (T2DM) and prediabetes and prevention of risk factors. Newly recruited 998 Lebanese individuals, in addition to 7,292 already available, were studied to investigate the prevalence of diabetes, prediabetes and their associated risk factors. Methods: Participants had fasting blood sugar and glycohemoglobin tests in addition to a lipid profile. Clinical and demographic information were obtained from a detailed questionnaire. The relationship between T2DM, its risk factors, and its complications were tested. Comparisons of these risk factors among diabetics, healthy, and coronary artery disease (CAD) patients were performed. Results: The prevalence of T2DM significantly increased with increasing BMI (p < 0.0001). Exercise activity level negatively correlated with the disease (p = 0.002), whereas the prevalence of T2DM (p < 0.0001) and CAD family history (p = 0.006) positively correlated with the affection status. The mean levels of triglycerides and LDL-C were significantly higher in diabetics (1.87; 1.35) compared to individuals with prediabetes (1.63; 1.26) and unaffected controls (1.49; 1.19). People with T2DM showed a significant decrease in HDL-C levels. A strong correlation of overall hyperlipidemia with the diabetes affection status was shown (p < 0.0001). Other comorbid factors such as hypertension (p < 0.0001) and self-reported obesity (p < 0.0001) were highly associated with T2DM and prediabetes. Reproductive health of women showed a strong correlation between giving birth to a baby with a high weight and the occurrence of T2DM and prediabetes later in life (p < 0.0001). Retinopathy and peripheral neuropathy were significantly correlated with diabetes and prediabetes (p < 0.0001). Conclusions: The present study shows an alarming prevalence of diabetes and prediabetes in the studied subgroups representative of the Lebanese population. en_US
dc.language.iso en en_US
dc.title Multivariate epidemiologic analysis of type 2 diabetes mellitus risks in the Lebanese population en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SAS en_US
dc.author.school SOM
dc.author.idnumber 201101727 en_US
dc.author.idnumber 200900035 en_US
dc.author.idnumber 200703831
dc.author.idnumber 201000156
dc.author.idnumber 201100314
dc.author.idnumber 200300001
dc.author.idnumber 201004815
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Diabetology and Metabolic Syndrome en_US
dc.journal.volume 6 en_US
dc.journal.issue 1 en_US
dc.article.pages 89 en_US
dc.keywords Type 2 diabetes en_US
dc.keywords Prediabetes en_US
dc.keywords Lebanon en_US
dc.keywords Risk factors en_US
dc.keywords Hyperlipidemia en_US
dc.keywords Coronary artery disease en_US
dc.identifier.ctation Ghassibe-Sabbagh, M., Deeb, M., Salloum, A. K., Mouzaya, F., Haber, M., Al-Sarraj, Y., ... & Ahdab, R. (2014). Multivariate epidemiologic analysis of type 2 diabetes mellitus risks in the Lebanese population. Diabetology & metabolic syndrome, 6(1), 89. en_US
dc.author.email michella.sabbagh@lau.edu.lb en_US
dc.author.email mary.deeb@lau.edu.lb en_US
dc.author.email angelique.salloum@lau.edu.lb
dc.author.email kamal.hirbli@lau.edu.lb
dc.author.email rechdi.ahdab@lau.edu.lb
dc.author.email pierre.zalloua@lau.edu.lb
dc.author.email rita.nemr@lau.edu.lb
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url http://download.springer.com/static/pdf/751/art%253A10.1186%252F1758-5996-6-89.pdf?originUrl=http%3A%2F%2Fdmsjournal.biomedcentral.com%2Farticle%2F10.1186%2F1758-5996-6-89&token2=exp=1465882756~acl=%2Fstatic%2Fpdf%2F751%2Fart%25253A10.1186%25252F1758-5996-6-89.pdf*~hmac=3abd87801fe68e30b969381f119cc89cd8436b58fee9a8d19f7d361cd64daa80 en_US

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