Supplementation of retrobulbar block with clonidine in vitreoretinal surgery

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dc.contributor.author Abi Nader, Elie
dc.contributor.author Yazbeck-Karam, Vanda G.
dc.contributor.author Siddik-Sayyid, Sahar M.
dc.contributor.author Barakat, Daisy E.
dc.contributor.author Karam, Hoda S.
dc.contributor.author Cherfane, Georges M.
dc.contributor.author Hajj Hussein, Jalal N.
dc.date.accessioned 2016-06-09T08:58:21Z
dc.date.available 2016-06-09T08:58:21Z
dc.date.copyright 2011 en_US
dc.date.issued 2016-06-09
dc.identifier.issn 0952-8180 en_US
dc.identifier.uri http://hdl.handle.net/10725/3993
dc.description.abstract Study Objective To evaluate the effect of clonidine when added to local anesthetics on duration of postoperative analgesia during retrobulbar block. Design Prospective, randomized controlled trial. Setting Operating room and Postanesthesia Care Unit of a university-affiliated hospital. Subjects 80 ASA physical status 1, 2, and 3 patients undergoing vitreoretinal surgery with or without scleral buckling. Interventions Patients in the control group (n = 40) received a retrobulbar block with 4.5 mL of lidocaine-bupivacaine and 0.5 mL of saline. Clonidine group patients (n = 40) received 4.5 mL of lidocaine-bupivacaine and 0.5 μg/kg of clonidine in a 0.5 mL volume. Measurements The time to first analgesic request, frequency of postoperative pain, and number of postoperative analgesic requests per patient were assessed. Main Results 37 patients in the control group (92.5%) versus 24 patients (60%) in the clonidine group reported pain postoperatively (P = 0.001), with a shorter time to first analgesic request noted in the control group (4.9 ± 3 vs 11.9 ± 5.3 hrs; P < 0.001). The median number of postoperative analgesic requests per patient during the first 24 hours was higher in the control group than the clonidine group [2 (0-3) vs. 1 (0-3); P < 0.001]. Conclusions The addition of clonidine 0.5 μg/kg to the local anesthetics of a retrobulbar block for vitreoretinal surgery decreases the frequency of postoperative pain and prolongs the time of analgesia. en_US
dc.language.iso en en_US
dc.title Supplementation of retrobulbar block with clonidine in vitreoretinal surgery en_US
dc.type Article en_US
dc.description.version Published en_US
dc.title.subtitle effect on postoperative pain en_US
dc.author.school SOM en_US
dc.author.idnumber 201004801 en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Journal of Clinical Anesthesia en_US
dc.journal.volume 23 en_US
dc.journal.issue 5 en_US
dc.article.pages 393-397 en_US
dc.keywords Anesthesia, regional en_US
dc.keywords Clonidine en_US
dc.keywords Eye surgery en_US
dc.keywords Postoperative pain en_US
dc.keywords Retrobulbar block en_US
dc.keywords Vitreoretinal surgery en_US
dc.identifier.doi http://dx.doi.org/10.1016/j.jclinane.2010.12.014 en_US
dc.identifier.ctation Yazbeck-Karam, V. G., Siddik-Sayyid, S. M., Nader, E. L. A., Barakat, D. E., Karam, H. S., Cherfane, G. M., ... & Aouad, M. T. (2011). Supplementation of retrobulbar block with clonidine in vitreoretinal surgery: effect on postoperative pain. Journal of clinical anesthesia, 23(5), 393-397. en_US
dc.author.email elie.abinader@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url http://www.sciencedirect.com/science/article/pii/S0952818011002029 en_US

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