Diagnostic considerations for Novel Influenza A (H1N1)

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dc.contributor.author Sheikh-Taha, Marwan
dc.contributor.author Eiland III, Edward H.
dc.contributor.author Han, Jian
dc.contributor.author Lindgren, Willliam
dc.contributor.author Macandrew, Thomas
dc.contributor.author English, Ali Hassoun
dc.date.accessioned 2016-06-02T13:08:34Z
dc.date.available 2016-06-02T13:08:34Z
dc.date.copyright 2012 en_US
dc.date.issued 2016-06-02
dc.identifier.citation Sheikh-Taha, M., Eiland E, Han J., Lindgren w., Macandrew English T., Hassoun A. (2012). Diagnostic considerations for novel influenza A (H1N1): International journal of pharmacy and pharmaceutical sciences,4 Suppl.1,73-75
dc.identifier.issn 0975-1491 en_US
dc.identifier.uri http://hdl.handle.net/10725/3937
dc.description.abstract Background: The emergence of novel swine-origin influenza A (H1N1) virus (S-OIV) infection represents a significant pandemic threat. Rapid and accurate diagnosis will enhance treatment and containment efforts. Methods: Ninety eight patients with influenza-like illness meeting the CDC’s guidelines for screening were tested with the rapid influenza test. Positive samples for influenza A were tested with real-time PCR (RT-PCR). Subsequently, all samples were tested using Target Enriched Multiplex Polymerase Chain Reaction (Tem-PCR). Results: Rapid influenza tests Conclusion: Clinical judgment should be applied when interpreting the results of the available S-OIV tests. A confirmatory and validated test for SOIV is urgently needed. confirmed 30 influenza A cases, 1 of influenza B, and resulted 67 negatives. The 30 samples positive for influenza A were tested using RT-PCR assay, which revealed 2 cases of seasonal influenza A, 7 cases of S-OIV, and 21 negatives for influenza infection. The TemPCR confirmed 1 of the seasonal influenza A cases but found the second case to be S-OIV. Tem-PCR confirmed the findings of RT-PCR in 3 of the SOIV cases but reported 4 of the cases negative for influenza. Additionally, Tem-PCR found 3 of the cases that were negative per RT-PCR were positive for S-OIV. The remainders were confirmed negative for influenza yet one was positive for adenovirus. The lone case of influenza B was confirmed with Tem-PCR. Among the 67 cases that were negative based on rapid influenza tests, Tem-PCR confirmed en_US
dc.language.iso en en_US
dc.title Diagnostic considerations for Novel Influenza A (H1N1) en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOP en_US
dc.author.idnumber 199410150 en_US
dc.author.department Pharmacy Practice Department en_US
dc.description.embargo N/A en_US
dc.relation.journal International Journal of Pharmacy and Pharmaceutical Sciences en_US
dc.journal.volume 4, Suppl 1 en_US
dc.article.pages 73-75 en_US
dc.keywords Swine flu en_US
dc.keywords Novel influenza A (H1N1) en_US
dc.keywords RT-PCR en_US
dc.keywords Tem-PCR en_US
dc.identifier.ctation Sheikh-Taha, M., Eiland III, E. H., Han, J., Lindgren, W., Macandrew, T., & English, A. H. (2012). Diagnostic considerations for novel influenza A (H1N1). International journal of pharmacy and pharmaceutical sciences, 4 (Suppl.1), 73-75. en_US
dc.author.email marwan.taha@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url http://www.ijppsjournal.com/Vol4Suppl1/2931.pdf en_US
dc.orcid.id https://orcid.org/0000-0002-8037-1201 en_US

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