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A catalytic asymmetric synthesis of 5,5-dimethylproline

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dc.contributor.author Elaridi, Jomana
dc.contributor.author Jackson, W. Roy
dc.contributor.author Robinson, Andrea J.
dc.date.accessioned 2015-12-22T09:32:28Z
dc.date.available 2015-12-22T09:32:28Z
dc.date.copyright 2005
dc.date.issued 2015-12-22
dc.identifier.issn 1362-511X en_US
dc.identifier.uri http://hdl.handle.net/10725/2869
dc.description.abstract The methyl ester derivative of commercially available N-acetyl-allylglycine readily undergoes cross-metathesis with 2-methylbut-2-ene and ruthenium–alkylidene catalyst to afford the prenylglycine derivative. Acid-catalysed cyclisation then affords 5,5-dimethylproline in near quantitative yield and enantioselectivity. en_US
dc.language.iso en en_US
dc.title A catalytic asymmetric synthesis of 5,5-dimethylproline en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SAS en_US
dc.author.idnumber 201100947 en_US
dc.author.woa N/A en_US
dc.author.department Natural Sciences en_US
dc.description.embargo N/A en_US
dc.relation.journal Tetrahedron: Asymmetry en_US
dc.journal.volume 11 en_US
dc.journal.issue 6 en_US
dc.article.pages 2025-2029 en_US
dc.identifier.doi http://dx.doi.org/10.1016/j.tetasy.2005.05.003
dc.identifier.ctation Elaridi, J., Jackson, W. R., & Robinson, A. J. (2005). A catalytic asymmetric synthesis of 5, 5-dimethylproline. Tetrahedron: Asymmetry, 16(11), 2025-2029. en_US
dc.author.email jomana.aridi@lau.edu.lb
dc.identifier.url http://www.sciencedirect.com/science/article/pii/S0957416605003411


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