Installation of reversible, metathesis-active tethers into linear peptide sequences can be used to promote formation of cyclic peptide amides and esters.
Citation:
Illesinghe, J., Guo, C. X., Garland, R., Ahmed, A., Van Lierop, B., Elaridi, J., ... & Robinson, A. J. (2009). Metathesis assisted synthesis of cyclic peptides. Chemical Communications, (3), 295-297.