Abstract:
Bis-dicarba analogues of native dicystine-containing α-conotoxin Rg1A, an analgesic peptide isolated from cone snail venom, were constructed on resin using a regioselective metathesis–hydrogenation strategy.
Citation:
Robinson, A. J., van Lierop, B. J., Garland, R. D., Teoh, E., Elaridi, J., Illesinghe, J. P., & Jackson, W. R. (2009). Regioselective formation of interlocked dicarba bridges in naturally occurring cyclic peptide toxins using olefin metathesis. Chemical Communications, (28), 4293-4295.
