Cancer cell resistance mechanisms

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dc.contributor.author Al-Dimassi, S.
dc.contributor.author Abou-Antoun, T.
dc.contributor.author El-Sibai, M.
dc.date.accessioned 2015-12-18T07:20:57Z
dc.date.available 2015-12-18T07:20:57Z
dc.date.copyright 2014
dc.date.issued 2015-12-18
dc.identifier.issn 1699-048X en_US
dc.identifier.uri http://hdl.handle.net/10725/2847
dc.description.abstract Cancer is a leading cause of death worldwide accounting to 13 % of all deaths. One of the main causes behind the failure of treatment is the development of various therapy resistance mechanisms by the cancer cells leading to the recurrence of the disease. This review sheds a light on some of the mechanisms developed by cancer cells to resist therapy as well as some of the structures involved such as the ABC members’ involvement in chemotherapy resistance and MET and survivin overexpression leading to radiotherapy resistance. Understanding those mechanisms will enable scientists to overcome resistance and possibly improve treatment and disease prognosis en_US
dc.language.iso en en_US
dc.title Cancer cell resistance mechanisms en_US
dc.type Article en_US
dc.description.version Published en_US
dc.title.subtitle A mini review en_US
dc.author.school SAS en_US
dc.author.school SOP
dc.author.idnumber 201005279 en_US
dc.author.idnumber 200703859
dc.author.woa N/A en_US
dc.author.department Natural Sciences en_US
dc.description.embargo N/A en_US
dc.relation.journal Clinical and Translational Oncology en_US
dc.journal.volume 16 en_US
dc.journal.issue 6 en_US
dc.article.pages 511-516 en_US
dc.keywords Cancer en_US
dc.keywords Chemotherapy resistance en_US
dc.keywords Multiple drug resistance en_US
dc.keywords Radiotherapy resistance en_US
dc.keywords Immunotherapy resistance and cancer stem cells en_US
dc.identifier.doi http://dx.doi.org/10.1007/s12094-014-1162-1 en_US
dc.identifier.ctation Al-Dimassi, S., Abou-Antoun, T., & El-Sibai, M. (2014). Cancer cell resistance mechanisms: a mini review. Clinical and Translational Oncology, 16(6), 511-516. en_US
dc.author.email tamara.abouantoun@lau.edu.lb
dc.author.email mirvat.elsibai@lau.edu.lb
dc.identifier.url http://link.springer.com/article/10.1007%2Fs12094-014-1162-1

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