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Tragopogon porrifolius improves serum lipid profile and increases short-term satiety in rats

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dc.contributor.author Zeeni, Nadine
dc.contributor.author Daher, Costantine F.
dc.contributor.author Mroueh, Mohamad
dc.contributor.author Saab, Lea
dc.date.accessioned 2015-12-15T13:29:15Z
dc.date.available 2015-12-15T13:29:15Z
dc.date.copyright 2013
dc.date.issued 2015-12-15
dc.identifier.issn 0195-6663 en_US
dc.identifier.uri http://hdl.handle.net/10725/2811
dc.description.abstract Tragopogon porrifolius (white salsify) is an edible plant commonly used in folk medicine in Lebanon and neighbouring countries. This study investigates the effect of the aqueous extract of the aerial part of T. porrifolius on lipemia and appetite regulation using a rat model. Food intake, abdominal fat percentage, blood lipid profile, liver weight and liver enzymes were assessed following 4 weeks of extract intake via drinking water (50, 100, or 250 mg/kg body weight) in standard high-carbohydrate and high-fat dietary conditions. In a separate study, the short term effect of a preload of T. porrifolius extract on food intake was evaluated. Results showed that consumption of the plant extract for a period of four weeks resulted in a marked improvement of the lipid profile (triglycerides, total cholesterol, LDL and HDL cholesterol). Body weight, food intake and intra-abdominal fat were also lower in animals given the plant extract (100 and 250 mg/kg). In addition, T. porrifolius extract preload produced a dose dependent decrease in food intake observed over 24 h. The intake of T. porrifolius aqueous extract therefore improved lipemia and increased satiety in rats with no visible adverse effects. en_US
dc.language.iso en en_US
dc.title Tragopogon porrifolius improves serum lipid profile and increases short-term satiety in rats en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SAS en_US
dc.author.idnumber 199190130 en_US
dc.author.idnumber 201000400
dc.author.idnumber 199590020
dc.author.woa N/A en_US
dc.author.department Natural Sciences en_US
dc.description.embargo N/A en_US
dc.relation.journal Appetite en_US
dc.journal.volume 72 en_US
dc.journal.issue 1 en_US
dc.article.pages 1-7 en_US
dc.keywords Tragopogon porrifolius en_US
dc.keywords Satiety en_US
dc.keywords High-fat diet en_US
dc.keywords Cholesterol en_US
dc.keywords Lipid profile en_US
dc.identifier.doi http://dx.doi.org/10.1016/j.appet.2013.09.023 en_US
dc.identifier.ctation Zeeni, N., Daher, C. F., Saab, L., & Mroueh, M. (2014). Tragopogon porrifolius improves serum lipid profile and increases short-term satiety in rats. Appetite, 72, 1-7. en_US
dc.author.email nadine.zeeni@lau.edu.lb
dc.author.email cdaher@lau.edu.lb
dc.author.email mmroueh@lau.edu.lb
dc.identifier.url http://www.sciencedirect.com/science/article/pii/S0195666313004054


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