Pretreatment assessment of hepatocellular carcinoma: expert consensus statement

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dc.contributor.author Vauthey, Jean-Nicolas
dc.contributor.author Dixon, Elijah
dc.contributor.author Abdalla, Eddie
dc.contributor.author Helton, Scott
dc.contributor.author Pawlik, Timothy
dc.contributor.author Taouli, Bachir
dc.contributor.author Brouquet, Antoine
dc.contributor.author Adams, Reid
dc.date.accessioned 2015-11-19T09:30:15Z
dc.date.available 2015-11-19T09:30:15Z
dc.date.copyright 2010
dc.date.issued 2015-11-19
dc.identifier.issn 1365-182X en_US
dc.identifier.uri http://hdl.handle.net/10725/2625
dc.description.abstract Staging of hepatocellular carcinoma (HCC) is complex and relies on multiple factors including tumor extent and hepatic function. No single staging system is applicable to all patients with HCC. The staging of the American Joint Committee on Cancer / International Union for Cancer Control should be used to predict outcome following resection or liver transplantation. The Barcelona Clinic Liver Cancer scheme is appropriate in patients with advanced HCC not candidate for surgery. Dual phase computed tomography or magnetic resonance imaging can be used for pretreatment assessment of tumor extent but the accuracy of these methods remains poor to characterize <1 cm lesions. Assessment of tumor response should not rely only on tumor size and new imaging methods are available to evaluate response to therapy in HCC patients. Liver volumetry is part of the preoperative assessment of patients with HCC candidate for resection as it reflects liver function. Preoperative portal vein embolization is indicated in patients with small future liver remnant (≤ 20% in normal liver; ≤ 40% in fibrotic or cirrhotic liver). Tumor size is not a contraindication to liver resection. Liver resection can be proposed in selected patients with multifocal HCC. Besides tumor extent, surgical resection of HCC may be performed in selected patients with chronic liver disease. en_US
dc.language.iso en en_US
dc.title Pretreatment assessment of hepatocellular carcinoma: expert consensus statement en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOM en_US
dc.author.idnumber 201100945 en_US
dc.author.woa N/A en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal HPB en_US
dc.journal.volume 12 en_US
dc.journal.issue 5 en_US
dc.article.pages 289-299 en_US
dc.keywords Consensus conference en_US
dc.keywords Staging en_US
dc.keywords Portal vein embolization en_US
dc.keywords Liver function en_US
dc.keywords Hepatocellular cancer en_US
dc.keywords Hepatoma en_US
dc.keywords Surgery en_US
dc.keywords Chemotherapy en_US
dc.keywords Radiotherapy en_US
dc.keywords Chemoembolization en_US
dc.identifier.doi http://dx.doi.org/10.1111/j.1477-2574.2010.00181.x en_US
dc.identifier.ctation Vauthey, J. N., Dixon, E., Abdalla, E. K., Helton, W. S., Pawlik, T. M., Taouli, B., ... & Adams, R. B. (2010). Pretreatment assessment of hepatocellular carcinoma: expert consensus statement. HPB, 12(5), 289-299. en_US
dc.author.email eddie.abdalla@lau.edu.lb
dc.identifier.url http://onlinelibrary.wiley.com/doi/10.1111/j.1477-2574.2010.00181.x/full

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