Hepatic Resection for Gastrointestinal Stromal Tumor Liver Metastases

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dc.contributor.author Zalinski, Stephanie
dc.contributor.author Palavecino, Martin
dc.contributor.author Abdalla, Eddie
dc.date.accessioned 2015-11-19T07:12:00Z
dc.date.available 2015-11-19T07:12:00Z
dc.date.copyright 2009
dc.date.issued 2015-11-19
dc.identifier.issn 0889-8588 en_US
dc.identifier.uri http://hdl.handle.net/10725/2609
dc.description.abstract Liver resection is the preferred treatment for gastrointestinal stromal tumor liver metastases (GIST LMs) when complete resection can be achieved. Major and extended hepatic resections can be safely performed, and using modern techniques, an increasing proportion of patients with GIST LMs are candidates for potentially curative therapy. The combination of tyrosine kinase inhibitor therapy (eg, imatinib) with surgery seems to improve outcome, and although prospective data are lacking, a short neoadjuvant course (6 months) of imatinib therapy followed by resection may improve patient selection for surgery and outcome from treatment. Postoperative therapy with imatinib is generally advised, although the duration of such therapy is not yet clearly defined. These questions may formulate the basis for future prospective studies of imatinib with complete resection of GIST LMs. en_US
dc.language.iso en en_US
dc.title Hepatic Resection for Gastrointestinal Stromal Tumor Liver Metastases en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOM en_US
dc.author.idnumber 201100945 en_US
dc.author.woa N/A en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Hematology/Oncology Clinics of North America en_US
dc.journal.volume 23 en_US
dc.journal.issue 1 en_US
dc.article.pages 115-127 en_US
dc.keywords Gastrointestinal stromal tumor en_US
dc.keywords Liver metastasis en_US
dc.keywords Liver resection en_US
dc.keywords Tyrosine kinase inhibitor en_US
dc.keywords Imatinib en_US
dc.keywords Extended hepatectomy en_US
dc.keywords Liver volumetry en_US
dc.keywords Portal vein embolization en_US
dc.identifier.doi http://dx.doi.org/10.1016/j.hoc.2008.11.001 en_US
dc.identifier.ctation Zalinski, S., Palavecino, M., & Abdalla, E. K. (2009). Hepatic resection for gastrointestinal stromal tumor liver metastases. Hematology/oncology clinics of North America, 23(1), 115-127. en_US
dc.author.email eddie.abdalla@lau.edu.lb
dc.identifier.url http://www.sciencedirect.com/science/article/pii/S0889858808001731

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