Curable metastatic colorectal cancer

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dc.contributor.author Abdalla, Eddie
dc.contributor.author Berri, Richard
dc.date.accessioned 2015-11-17T10:16:05Z
dc.date.available 2015-11-17T10:16:05Z
dc.date.copyright 2009
dc.date.issued 2015-11-17
dc.identifier.issn 1523-3790 en_US
dc.identifier.uri http://hdl.handle.net/10725/2597
dc.description.abstract “Cure” for patients with stage IV colorectal cancer remains elusive, but for a growing subset of patients with colorectal liver metastases (CLMs), cure (ie, > 10-year survival without evidence of disease) is achieved in at least 17% of resected patients. Candidates for resection include those with limited and in some cases extensive hepatic disease, and in highly selected cases, patients with extrahepatic disease. Number, size, and bilaterality of CLMs no longer stand as absolute contraindications to surgery. Chemotherapy has further advanced the field of surgery for CLMs, enabling an additional group of patients who present with unresectable disease to undergo surgery after downsizing with chemotherapy. Modern surgical techniques and liver preparation allow resection after chemotherapy, with excellent results. This article summarizes the current multidisciplinary approach to treatment of CLMs. The definition of resectability, conversion of unresectable CLMs to resectable ones, advances in surgical techniques, advances in chemotherapy, and predictors of outcome are detailed en_US
dc.language.iso en en_US
dc.title Curable metastatic colorectal cancer en_US
dc.type Article en_US
dc.description.version Published en_US
dc.title.subtitle Recommended paradigms en_US
dc.author.school SOM en_US
dc.author.idnumber 201100945 en_US
dc.author.woa N/A en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Current Oncology Reports en_US
dc.journal.volume 11 en_US
dc.journal.issue 3 en_US
dc.article.pages 200-208 en_US
dc.identifier.doi http://dx.doi.org/10.1007/s11912-009-0029-z en_US
dc.identifier.ctation Berri, R. N., & Abdalla, E. K. (2009). Curable metastatic colorectal cancer: recommended paradigms. Current oncology reports, 11(3), 200-208. en_US
dc.author.email eddie.abdalla@lau.edu.lb

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