Strategies for Resection Using Portal Vein Embolization: Hepatocellular Carcinoma and Hilar Cholangiocarcinoma

LAUR Repository

Show simple item record

dc.contributor.author Anaya, Daniel
dc.contributor.author Blazer, Dan
dc.contributor.author Abdalla, Eddie
dc.date.accessioned 2015-11-16T12:34:03Z
dc.date.available 2015-11-16T12:34:03Z
dc.date.copyright 2008
dc.date.issued 2015-11-16
dc.identifier.issn 0739-9529 en_US
dc.identifier.uri http://hdl.handle.net/10725/2583
dc.description.abstract Preoperative portal vein embolization (PVE) is increasingly used to optimize the volume and function of the future liver remnant (FLR) and to reduce the risk for complications of major hepatectomy for hepatocellular carcinoma (HCC) or hilar cholangiocarcinoma (CCA). In patients with HCC who are candidates for extended hepatectomy and in patients with HCC and well-compensated cirrhosis who are being considered for major hepatectomy, FLR volumetry is routinely performed, and PVE is employed in selected cases to optimize the volume and function of the FLR prior to surgery. Similarly, in patients with hilar CCA who are candidates for extended hepatectomy, careful preoperative preparation using biliary drainage, FLR volumetry, and PVE optimizes the volume and function of the FLR prior to surgery. Appropriate use of PVE has led to improved postoperative outcomes after major hepatectomy for these diseases and oncological outcomes similar to those in patients who undergo resection without PVE. Specific indications for PVE are being clarified. FLR volumetry is necessary for proper selection of patients for PVE. Analysis of the degree of hypertrophy of the FLR after PVE (a dynamic test of liver regeneration) complements analysis of the pre-PVE FLR volume (a static test). Together, FLR degree of hypertrophy and FLR volume are the best predictors of outcome after major hepatectomy in an individual patient, regardless of the degree of underlying liver disease. This article synthesizes the literature on the approach to patients with HCC and CCA who are candidates for major hepatectomy. The rationale and indications for FLR volumetry and PVE and outcomes following PVE and major hepatectomy for HCC and CCA are discussed. en_US
dc.language.iso en en_US
dc.title Strategies for Resection Using Portal Vein Embolization: Hepatocellular Carcinoma and Hilar Cholangiocarcinoma en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOM en_US
dc.author.idnumber 201100945 en_US
dc.author.woa N/A en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Seminars interventional in radiology en_US
dc.journal.volume 25 en_US
dc.journal.issue 2 en_US
dc.article.pages 110-122 en_US
dc.keywords Portal vein embolization en_US
dc.keywords Liver volumetry en_US
dc.keywords Future liver remnant en_US
dc.keywords Hepatocellular carcinoma en_US
dc.keywords Hilar cholangiocarcinoma en_US
dc.identifier.doi http://dx.doi.org/10.1055/s-2008-1076684 en_US
dc.identifier.ctation Anaya, D. A., Blazer III, D. G., & Abdalla, E. K. (2008, June). Strategies for resection using portal vein embolization: hepatocellular carcinoma and hilar cholangiocarcinoma. In Seminars in interventional radiology (Vol. 25, No. 2, p. 110). Thieme Medical Publishers. en_US
dc.identifier.url https://www.thieme-connect.com/products/ejournals/html/10.1055/s-2008-1076684

Files in this item

This item appears in the following Collection(s)

Show simple item record

Search LAUR

Advanced Search


My Account