New paradigm in the management of liver-only metastases from colorectal cancer

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dc.contributor.author Donadon, Matteo
dc.contributor.author Ribero, Dario
dc.contributor.author Morris-Stiff, Gareth
dc.contributor.author Abdalla, Eddie
dc.contributor.author Vauthey, Nicolas
dc.date.accessioned 2015-11-16T07:29:02Z
dc.date.available 2015-11-16T07:29:02Z
dc.date.copyright 2007
dc.date.issued 2015-11-16
dc.identifier.citation Donadon, M., Ribero, D., Morris-Stiff, G., Abdalla, E. K., & Vauthey, J. N. (2007). New paradigm in the management of liver-only metastases from colorectal cancer. Gastrointest Cancer Res, 1(1), 20-27.
dc.identifier.issn 1934-7820 en_US
dc.identifier.uri http://hdl.handle.net/10725/2571
dc.description.abstract For patients with colorectal liver metastases, hepatic resection is the treatment of choice, and the 5-year survival rate following surgery now exceeds 50%. Timely multidisciplinary and multimodality approaches that may include preoperative systemic chemotherapy, preoperative portal vein embolization, extended hepatic resection, and two-stage hepatectomy, have enabled a large proportion of patients to undergo potentially curative treatment. The definition of resectability has shifted from a focus on tumor characteristics, such as tumor number and size, to determination of whether both intrahepatic and extrahepatic disease can be completely resected and whether such an approach is appropriate from an oncologic standpoint for a given patient. Future identification of molecular factors may aid in predicting prognosis of patients with colorectal liver metastases and in improving the selection of patients most likely to benefit from surgery. Hepatobiliary surgeons and medical oncologists should work together to individualize treatment strategies to maximize long-term survival in patients with colorectal liver metastases. en_US
dc.language.iso en en_US
dc.title New paradigm in the management of liver-only metastases from colorectal cancer en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOM en_US
dc.author.idnumber 201100945 en_US
dc.author.woa N/A en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Gastrointestinal cancer research en_US
dc.journal.volume 1 en_US
dc.journal.issue 1 en_US
dc.article.pages 20-27 en_US
dc.author.email eddie.abdalla@lau.edu.lb

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