Staging classifications for hepatocellular carcinoma

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dc.contributor.author Van Deusen, Mathew
dc.contributor.author Abdalla, Eddie
dc.contributor.author Vauthey, Nicolas
dc.date.accessioned 2015-11-11T14:00:49Z
dc.date.available 2015-11-11T14:00:49Z
dc.date.copyright 2014
dc.date.issued 2015-11-11
dc.identifier.issn 1473-7159 en_US
dc.identifier.uri http://hdl.handle.net/10725/2538
dc.description.abstract Evaluation and treatment of patients with hepatocellular carcinoma is dependent on accurate staging. Tumor-specific factors and the degree of underlying liver disease must be considered when evaluating patients with hepatocellular carcinoma. Clinical staging classification systems based on preinterventional data are predictive of survival and influence patient selection for various therapeutic modalities. Pathologic staging systems accurately assess prognosis and influence additional treatment post resection. The various staging systems for hepatocellular carcinoma are reviewed in detail. The benefits and limitations of these classification systems are discussed in this review. Considerable controversy remains over which classification system provides the optimum staging of hepatocellular carcinoma. The revised American Joint Committee on Cancer/International Union Against Cancer emphasizes the importance of major vascular and microvascular invasion as independent predictors of death and the negative impact of severe fibrosis/cirrhosis on survival following resection of hepatocellular carcinoma. As such, it is currently the most accurate staging system in this group of patients. Its applicability in those patients who are not candidates for resection is uncertain. en_US
dc.language.iso en en_US
dc.title Staging classifications for hepatocellular carcinoma en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOM en_US
dc.author.idnumber 201100945 en_US
dc.author.woa N/A en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Expert Review of Molecular Diagnostics en_US
dc.journal.volume 5 en_US
dc.journal.issue 3 en_US
dc.article.pages 377-383 en_US
dc.keywords Classification schemes en_US
dc.keywords Hepatocellular carcinoma en_US
dc.keywords Revised AJCC/UICC staging classification en_US
dc.keywords Staging en_US
dc.identifier.doi http://dx.doi.org/10.1586/14737159.5.3.377 en_US
dc.identifier.ctation Van Deusen, M. A., Abdalla, E. K., Vauthey, J. N., & Roh, M. S. (2005). Staging classifications for hepatocellular carcinoma. en_US
dc.author.email eddie.abdalla@lau.edu.lb

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