Body surface area and body weight predict total liver volume in Western adults

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dc.contributor.author Abdalla, Eddie
dc.contributor.author Vauthey, Nicolas
dc.contributor.author Doherty, Dorota
dc.contributor.author Gertsch, Philippe
dc.contributor.author Fenstermacher, Marc
dc.contributor.author Loyer, Evelyne
dc.contributor.author Leurt, Jan
dc.contributor.author Materne, Roland
dc.contributor.author Wang, Xuemei
dc.contributor.author Encarnacion, Arthur
dc.contributor.author Herron, Delise
dc.contributor.author Mathey, Christian
dc.contributor.author Ferrari, Giovanni
dc.contributor.author Charnsangavej, Chusilp
dc.contributor.author Do, Kim-Anh
dc.contributor.author Denys, Alban
dc.date.accessioned 2015-11-10T09:58:25Z
dc.date.available 2015-11-10T09:58:25Z
dc.date.copyright 2002
dc.date.issued 2015-11-10
dc.identifier.issn 1527-6465 en_US
dc.identifier.uri http://hdl.handle.net/10725/2511
dc.description.abstract Computed tomography (CT) is used increasingly to measure liver volume in patients undergoing evaluation for transplantation or resection. This study is designed to determine a formula predicting total liver volume (TLV) based on body surface area (BSA) or body weight in Western adults. TLV was measured in 292 patients from four Western centers. Liver volumes were calculated from helical computed tomographic scans obtained for conditions unrelated to the hepatobiliary system. BSA was calculated based on height and weight. Each center used a different established method of three-dimensional volume reconstruction. Using regression analysis, measurements were compared, and formulas correlating BSA or body weight to TLV were established. A linear regression formula to estimate TLV based on BSA was obtained: TLV = −794.41 + 1,267.28 × BSA (square meters; r2 = 0.46; P < .0001). A formula based on patient weight also was derived: TLV = 191.80 + 18.51 × weight (kilograms; r2 = 0.49; P < .0001). The newly derived TLV formula based on BSA was compared with previously reported formulas. The application of a formula obtained from healthy Japanese individuals underestimated TLV. Two formulas derived from autopsy data for Western populations were similar to the newly derived BSA formula, with a slight overestimation of TLV. In conclusion, hepatic three-dimensional volume reconstruction based on helical CT predicts TLV based on BSA or body weight. The new formulas derived from this correlation should contribute to the estimation of TLV before liver transplantation or major hepatic resection. en_US
dc.language.iso en en_US
dc.title Body surface area and body weight predict total liver volume in Western adults en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOM en_US
dc.author.idnumber 201100945 en_US
dc.author.woa N/A en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Liver Transplantation en_US
dc.journal.volume 8 en_US
dc.journal.issue 3 en_US
dc.article.pages 233-240 en_US
dc.identifier.doi http://dx.doi.org/10.1053/jlts.2002.31654 en_US
dc.identifier.ctation Vauthey, J. N., Abdalla, E. K., Doherty, D. A., Gertsch, P., Fenstermacher, M. J., Loyer, E. M., ... & Denys, A. (2002). Body surface area and body weight predict total liver volume in Western adults. Liver transplantation, 8(3), 233-240. en_US
dc.author.email eddie.abdalla@lau.edu.lb
dc.identifier.url http://onlinelibrary.wiley.com/doi/10.1053/jlts.2002.31654/full

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