Psammoma bodies in cervicovaginal smears

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dc.contributor.author Zreik, Tony
dc.contributor.author Rutherford, Thomas
dc.date.accessioned 2015-10-06T09:04:39Z
dc.date.available 2015-10-06T09:04:39Z
dc.date.copyright 2001
dc.date.issued 2015-10-06
dc.identifier.issn 0029-7844 en_US
dc.identifier.uri http://hdl.handle.net/10725/2258
dc.description.abstract Objective: To estimate the prevalence of psammoma bodies in routine cervical cytology specimens and describe clinical diagnoses associated with them in pre- and postmenopausal women. Methods: We identified all reports that contained psammoma bodies from a retrospective review of 34,816 cytology reports over 4 consecutive years from the computerized pathology database at Yale New-Haven Medical Center. Slides were reviewed to confirm and qualify psammoma bodies. Medical records of women with psammoma bodies were reviewed and information on follow-up was collected. Results: We identified 18 women with psammoma bodies on their Papanicolaou smears. The median age was 49.5 years (range 17–78 years). Seven of eight postmenopausal women had gynecologic malignancies. Five presented with postmenopausal bleeding and had uterine serous or clear-cell carcinomas. One presented with a pelvic mass that was ovarian serous carcinoma. Another had a serous carcinoma of the fallopian tube with only psammoma bodies on Papanicolaou smears. Only one of the remaining 11 nonmalignant cases was a postmenopausal woman. Conclusion: The prevalence of psammoma bodies in consecutively screened Papanicolaou smears was 18 of 34,816. Psammoma bodies on Papanicolaou smears are ominous in postmenopausal women. Their presence in asymptomatic premenopausal women warrants further evaluation, but not necessarily surgical exploration en_US
dc.language.iso en en_US
dc.title Psammoma bodies in cervicovaginal smears en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOM en_US
dc.author.idnumber 200802707
dc.author.woa N/A en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Obstetrics & Gynecology en_US
dc.journal.volume 97 en_US
dc.journal.issue 5 en_US
dc.article.pages 693-695 en_US
dc.identifier.ctation Zreik, T. G., & Rutherford, T. J. (2001). Psammoma bodies in cervicovaginal smears. Obstetrics & Gynecology, 97(5), 693-695. en_US
dc.author.email tgzreik@lau.edu.lb
dc.identifier.url http://journals.lww.com/greenjournal/Abstract/2001/05000/Psammoma_Bodies_in_Cervicovaginal_Smears.9.aspx

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