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Browsing SOM - Scholarly Publications by Issue Date

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Browsing SOM - Scholarly Publications by Issue Date

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  • Extrahepatic Bile Duct Adenocarcinoma 
    Borghero, Yerko; Crane, Christopher; Szklaruk, Janio; Oyarzo, Mauricio; Curley, Steven; Pisters, Peter; Evans, Douglas; Abdalla, Eddie; Thomas, Melanie; Das, Prajnan; Wistuba, Ignacio; Krishnan, Sunil; Vauthey, Nicolas (2015-11-16)
    Background Patients with resected extrahepatic bile duct adenocarcinoma who have microscopically positive resection margins and/or pathologic locoregional nodal involvement (R1pN1) have a high-risk of locoregional recurrence, ...
  • Bevacizumab Improves Pathologic Response and Protects Against Hepatic Injury in Patients Treated With Oxaliplatin-Based Chemotherapy for Colorectal Liver Metastases 
    Ribero, David; Wang, Huamin; Donadon, Matteo; Zorzi, Daria; Thomas, Melanie; Eng, Cathy; Chang, David; Curley, Steven; Abdalla, Eddie; Ellis, Lee; Vauthey, Nicolas (2015-11-16)
    BACKGROUND. The current study evaluated the effect of bevacizumab added to fluoropyrimidine-plus-oxaliplatin (5FU/OX) chemotherapy for colorectal liver metastases (CLM) on the pathologic response and nontumorous liver ...
  • The Development and Characterization of a Human Midgut Carcinoid Cell Line 
    Van Burenn II, George; Rashid, Asif; Yang, Anthony; Abdalla, Eddie; Gray, Micheal; Liu, Wenbiao; Somicio, Ray; Fan, Fan; Camp, Ramsay; Yao, James; Ellis, Lee (2015-11-16)
    Purpose: Gastrointestinal neuroendocrine tumors (NET) are rare heterogeneous tumors that hypersecrete neuropeptides. The scarcity of good gastrointestinal NET models has limited the ability to study potential therapeutic ...
  • Liver-Directed Surgery for Metastatic Squamous Cell Carcinoma to the Liver 
    Pawlik, Timothy; Gleisner, Ana Luiza; Bauer, Todd; Reddy, Srinevas; Clary, Bryan; Martin, Robert; Scoggins, Charles; Tanabe, Kenneth; Michealson, James; Kooby, David; Staley, Charles; Schulick, Richard; Vauthey, Nicolas; Abdalla, Eddie; Curley, Steven; Choti, Micheal; Elias, Dominique (2015-11-16)
    Background The role of hepatic resection for metastatic squamous cell carcinoma (SCC) remains unknown. The current study evaluates the role of hepatic resection in patients with metastatic SCC to the liver. Methods Between ...
  • Outcomes of Liver Transplantation in 490 Patients with Hepatocellular Carcinoma 
    Vauthey, Nicolas; Ribero, Dario; Abdalla, Eddie; Jonas, Sven; Bharat, Ankit; Schumacher, Guido; Lerut, Jan; Chapman, William; Hemming, Alan; Neuhaus, Peter (2015-11-16)
    Background The aim of this study was to compare the ability of staging systems (American Joint Committee on Cancer/Union Internationale contre le Cancer [AJCC/UICC], Japanese TNM, Pittsburgh, United Network for Organ ...
  • Portal vein embolization before major hepatectomy and its effects on regeneration, resectability and outcome 
    Madoff, D.C.; Abdalla, Eddie; Donadon, M.; Loyer, E.M.; Vauthey, J.-N.; Ribero, D. (2015-11-16)
    Background: This study evaluated the safety of portal vein embolization (PVE), its impact on future liver remnant (FLR) volume and regeneration, and subsequent effects on outcome after liver resection. Methods: Records ...
  • Treatment of Large and Advanced Hepatocellular Carcinoma 
    Abdalla, Eddie; Denys, Alban; Hasegawa, Kiyoshi; Leung, Thomas; Makuushi, Masatoshi; Murthy, Ravi; Ribero, Dario; Zorzi, Daria; Vauthey, Nicolas; Torzilli, Guido (2015-11-16)
  • Preoperative Bevacizumab Does Not Significantly Increase Postoperative Complication Rates in Patients Undergoing Hepatic Surgery for Colorectal Cancer Liver Metastases 
    Kesmodel, Susan; Ellis, Lee; Lin, E.; Chang, George; Abdalla, Eddie; Kopetz, Scott; Vauthey, Jean-Nicolas; Rodriguez-Bigas, Miguel; Curley, Steven; Feig, Barry (2015-11-17)
    Purpose Although bevacizumab (BV) increases survival rates when used with chemotherapy (CTX) in patients who have metastatic colorectal cancer (CRC), an increase in wound complications has been observed in patients who ...
  • Association of Computed Tomography Morphologic Criteria With Pathologic Response and Survival in Patients Treated With Bevacizumab for Colorectal Liver Metastases 
    Shin Chun, Yun; Vauthey, Jean-Nicolas; Boonsirikamcha, Piyaporn; Maru, Dipen; Kopetz, Scott; Palavecino, Martin; Curley, Steven; Abdalla, Eddie; Kaur, Harmeet; Charnsangavej, Chusilp; Loyer, Evelyne (2015-11-17)
    Context The standard criteria used to evaluate tumor response, the Response Evaluation Criteria in Solid Tumors (RECIST), were developed to assess tumor shrinkage after cytotoxic chemotherapy and may be limited in assessing ...
  • One Hundred Years After “Carcinoid” 
    Yao, James; Hassan, Manal; Phan, Alexandria; Dagohy, Cecile; Leary, Colleen; Mares, Jeannette; Abdalla, Eddie; Fleming, Jason; Vauthey, Jean-Nicolas; Rashid, Asif; Evans, Douglas (2015-11-17)
    Purpose Neuroendocrine tumors (NETs) are considered rare tumors and can produce a variety of hormones. In this study, we examined the epidemiology of and prognostic factors for NETs, because a thorough examination of neither ...
  • Three Hundred and One Consecutive Extended Right Hepatectomies 
    Kishi, Yoji; Abdalla, Eddie; Chun, Yun Shin; Zorzi, Daria; Madoff, David; Wallace, Micheal; Curley, Steven; Vauthey, Jean-Nicolas (2015-11-17)
    Objective(s): This study aimed to determine the effect of preoperative liver volumetry on postoperative outcomes after extended right hepatectomy. Primary end point was to evaluate whether future liver remnant (FLR)/standardized ...
  • Borderline Resectable Pancreatic Cancer 
    Katz, Matthew; Pisters, Peter; Evans, Douglas; Sun, Charlotte; Lee, Jeffrey; Fleming, Jason; Vauthey, Jean-Nicolas; Abdalla, Eddie; Crane, Christopher (2015-11-17)
    Background Patients with borderline resectable pancreatic adenocarcinoma (PA) include those with localized disease who have tumor or patient characteristics that preclude immediate surgery. There is no optimal treatment ...
  • Chemotherapy With Bevacizumab Does Not Affect Liver Regeneration After Portal Vein Embolization in the Treatment of Colorectal Liver Metastases 
    Zorzi, Daria; Shin Chun, Yun; Madoff, David; Abdalla, Eddie; Vauthey, Jean-Nicolas (2015-11-17)
    Background Blockage of vascular endothelial growth factor (VEGF) in murine models has been shown to impair liver regeneration after partial hepatectomy. The aim of this study was to evaluate the effects of chemotherapy ...
  • Blood Neutrophil-to-Lymphocyte Ratio Predicts Survival in Patients with Colorectal Liver Metastases Treated with Systemic Chemotherapy 
    Abdalla, Eddie; Kishi, Yoji; Kopetz, Scott; Chun, Yun Shin; Palavecino, Martin; Vauthey, Jean-Nicolas (2015-11-17)
    Background Whether neutrophil-to-lymphocyte ratio (NLR) predicts survival of patients with colorectal liver metastases (CLM) treated with systemic chemotherapy remains unclear. Methods Clinicopathologic data were reviewed ...
  • Long-Term Survival After Multidisciplinary Management of Resected Pancreatic Adenocarcinoma 
    Katz, Matthew; Wang, Huamin; Fleming, Jason; Sun, Charlotte; Hwang, Rosa; Wolff, Robert; Varadhachary, Gauri; Abbruzzese, James; Crane, Christopher; Krishnan, Sunil; Vauthey, Jean-Nicolas; Abdalla, Eddie; Lee, Jeffrey; Pisters, Peter; Evans, Douglas (2015-11-17)
    Introduction Actual 5-year survival rates of 10–18% have been reported for patients with resected pancreatic adenocarcinoma (PC), but the use of multimodality therapy was uncommon in these series. We evaluated long-term ...
  • Preoperative Gemcitabine and Cisplatin Followed by Gemcitabine-Based Chemoradiation for Resectable Adenocarcinoma of the Pancreatic Head 
    Varadhachary, Gauri; Wolff, Robert; Crane, Christopher; Sun, Charlotte; Lee, Jeffrey; Pisters, Peter; Vauthey, Jean-Nicolas; Abdalla, Eddie; Wang, Huamin; Staerkel, Gregg; Ross, William; Tamm, Eric; Bhosale, Priya; Krishnan, Sunil; Das, Prajnan; Ho, Linus; Xiong, Henry; Abbruzzese, James; Evans, Douglas (2015-11-17)
    Purpose We conducted a phase II trial of preoperative gemcitabine and cisplatin chemotherapy in addition to chemoradiation (Gem-Cis-XRT) and pancreaticoduodenectomy (PD) for patients with stage I/II pancreatic adenocarci ...
  • Association between hypothyroidism and hepatocellular carcinoma 
    Hassan, Manal; Kaseb, Ahmed; Li, Donghui; Vauthey, Jean-Nicolas; Thomas, Melanie; Curley, Steven; Spitz, Margaret; Sherman, Steven; Abdalla, Eddie; Davila, Marta; Lozano, Richard; Hassan, Deena; Wenyaw, Chan; Brown, Thomas; Abbruzzese, James; Patt, Yehuda (2015-11-17)
    Thyroid hormones play an essential role in lipid mobilization, lipid degradation, and fatty acid oxidation. Hypothyroidism has been associated with nonalcoholic steatohepatitis; however, the association between thyroid ...
  • Aggressive Combined Modality Therapy for Recurrent Colorectal Cancer Involving the Duodenum and Pancreas 
    Overman, Micheal; Fogelman, David; Al-Kali, Aref; Crane, Christopher; Evans, Douglas; Abdalla, Eddie; Pisters, Peter; Kopetz, Scott; Eng, Cathy; Wolff, Robert (2015-11-17)
    We report 5 cases in which the recurrence of colorectal cancer (CRC) presented as a mass involving the duodenum and pancreas. The treatment approach for such recurrences is not standardized, and in particular, the benefits ...
  • Effect of different types of smoking and synergism with hepatitis C virus on risk of hepatocellular carcinoma in American men and women 
    Hassan, Manal; Spitz, Margaret; Thomas, Melanie; El-Deeb, Adel; Glover, Katrina; Nguyem, Nga; Chan, Wenyaw; Kaseb, Ahmed; Curley, Steven; Vauthey, Nicolas; Ellis, Lee; Abdalla, Eddie; Lozano, Richard; Patt, Yehuda; Brown, Thomas; Abbruzzese, James; Li, Donghui (2015-11-17)
    The International Agency for Research on Cancer has declared smoking to be a risk factor for hepatocellular carcinoma (HCC). However, passive exposure to cigarette smoke and use of noncigarette tobacco products on the risk ...
  • Comparison of Two Methods of Future Liver Remnant Volume Measurement 
    Shin Chun, Yun; Ribero, Dario; Abdalla, Eddie; Madoff, David; Mortenson, Melinda; Wei, Steven; Vauthey, Nicolas (2015-11-17)
    Background In liver transplantation, a minimum graft to patient body weight (BW) ratio is required for graft survival; in liver resection, total liver volume (TLV) calculated from body surface area (BSA) is used to determine ...

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