• Efficacy And Safety of Cannabidiol on Juvenile Diabetes Outcomes in Male Rats 

  Awkar, Nai (Lebanese American University, 2023-07-27)

  Background: Cannabidiol (CBD) is a major non-psychotomimetic cannabinoid found in the Cannabis sativa plant with several pharmacological effects. Juvenile Diabetes is a major chronic illness that affects the life of patients. ...
• Anticancer Effects of Lebanese Cannabis Oil Against in vivo and in vitro Models of Squamous Cell Carcinoma 

  Azar Atallah, Shirine (Lebanese American University, 2023-07-25)

  Cannabis sativa L. has a long history of use in traditional medicine for various ailments as an analgesic, anticonvulsant, hypnotic, tranquilizer, and anti-inflammatory agent. Emerging evidence in preclinical studies has ...
• Therapeutic Effect of Lebanese Cannabis Oil Extract in the Management of Sodium Orthovanadate-Induced Nephrotoxicity in Rats 

  Habchy, Chistabel (Lebanese American University, 2023-05-23)

  The current study investigated the therapeutic effect of Lebanese Cannabis oil extract against Sodium orthovanadate-induced nephrotoxicity. Sodium orthovanadate is a non-selective inhibitor of protein tyrosine phosphatases ...
• The Role of DJ-1 in the Glycation Process of Skin and Plasma Proteins in Mice Models 

  Abou Younes, Nour (Lebanese American University, 2023-05-18)

  The glycation reaction is a non-enzymatic reaction characterized by and spontaneous binding of sugar molecules and protein. This study focuses on the glycation process at the level of proteins. Protein glycation is initiated ...
• Efficacy of Lebanese Cannabis Oil Extract in the Treatment of Folic Acid-Induced Renal Fibrosis in Rats 

  Bylan, Diana (Lebanese American University, 2023-05-18)

  Kidney disease is a main contributor to mortality and morbidity worldwide. Renal fibrosis is the most common and final manifestation of chronic kidney disease. To date, there are no medications that target kidney cells or ...
• Identification and Characterization of a Novel Bacterial Species Found in the Lebanese Soil 

  Kyprianos, Shirine (Lebanese American University, 2022-12-30)

  The disruption of the soil's ecosystem causes a disturbance in microbial communities and leads to the emergence of dangerous resistant pathogens and most antibiotic resistance genes. An unknown bacterial strain was collected ...
• Novel Natural Based Chewable Lozenges for the Treatment of Erectile Dysfunction 

  Frem, Jean-Pierre (Lebanese American University, 2022-12-30)

  Chewable lozenges are easy to use, and highly flavored oral dosage forms used to deliver active ingredients, while providing high patient compliance rates. This work targets the development of chewable lozenges containing ...
• Potential Therapeutic Effects of Lebanese Cannabis oil in Female Mouse Models of Neuropsychiatric Disorders 

  Hatoum, Fatina (Lebanese American University, 2022-07-14)

  The Cannabis plant is the most versatile herbal remedy used for the treatment of various medical conditions, including pain, epilepsy, depression, anxiety, and post-traumatic stress disorder. Stress is a normal part of ...
• Barriers to the Implementation of a Unique Identifier and a Track and Trace System in the Lebanese Pharmaceutical Sector 

  Rached, Stephanie (Lebanese American University, 2022-05-23)

  Globalization of the pharmaceutical supply chain introduced many new challenges requiring innovative technologies to ensure patients’ access to safe and effective medicine. Adding a unique identifier and implementing a ...
• Efficacy of Cannabidiol Combination with Cisplatin or Paclitaxel against Platinum-Resistant Ovarian Cancer Cell Lines 

  Ismail, Jana (Lebanese American University, 2022-05-13)

  Cannabidiol (CBD) is one of the most abundant and commonly used cannabinoid of the Cannabis plant. Unlike tetrahydrocannabinol (THC), it lacks psychoactive properties, and thus it is considered to be a uniquely attractive ...
• Detection of Impurities in Acetaminophen Intravenous and Oral Formulations Available on the Lebanese Market 

  Rahme, Rita (Lebanese American University, 2022-01-27)

  Introduction: The presence of impurities in pharmaceutical formulations has been a concern worldwide. Acetaminophen is a commonly used drug for its analgesic and antipyretic properties. We report here a novel method for ...
• Efficacy and Toxicity of Hand Sanitizers 

  Zgheib, Rebecca (Lebanese American University, 2022-01-14)

  Since the outbreak of Coronavirus Disease 2019 (CoVID-19), the World Health Organization has suggested that alcohol-based hand sanitizers should be used in the absence of soap and water to prevent the spread of SARS-CoV2. This ...
• Evaluation Of Anti Thyroid Activity of Cannabis Sativa Oil Extract Against Levothyroxine Induced Hyperthyroidism in Mice 

  Al Sayed, Dania (Lebanese American University, 2021-12-14)

  Lebanese cannabis is well-known for its high quality and recreational value; yet little is known regarding its medical use. Hyperthyroidism affects approximately 1%-2% of the world population. Limited literature is available ...
• The Protective Effects of Daucus carota L. ssp. carota and Cannabis sativa L. Extracts against Cisplatin Induced Nephrotoxicity in Animal Models 

  Al Toufaily, Sahar (Lebanese American University, 2021-07-30)

  Cisplatin is a standard antineoplastic drug that has been incorporated in many firstline chemotherapy regimens for the treatment of solid tumors such as, advanced ovarian, lung, head and neck, testicular and bladder. ...
• Anti-cancer Evaluation of Lebanese Cannabis Oil Extract on Lung and Breast Cancer Cells 

  Saliba, Jane (Lebanese American University, 2021-05-31)

  Cannabis sativa L. is one of the oldest plants used in traditional medicine. Lebanese cannabis is recognized around the world for its quality and recreational use; however, little is known about its medicinal importance. ...
• Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells 

  Al Sayyed, Fatima (Lebanese American University, 2021-08-04)

  Neuroblastoma is the most common malignant tumor of infancy and accounts for 10% of all childhood cancers. The high biological and clinical heterogeneity of this tumor leads to differences in clinical outcomes ranging from ...
• Development and Characterization of Mucoadhesive Thin Film as an Oral Mucosal Drug Delivery System of Carbinoxamine Maleate 

  El Hajj, Antonio (Lebanese American University, 2021-08-02)

  Objective: Thin film (TF) is an oral mucosal drug delivery system that disintegrates and dissolves the drug rapidly when placed on any oral mucosal tissue. This work aimed to develop and characterize TF containing carbinoxamine ...
• The Effect of Formulation Parameters on the Physical Properties and In-Vitro Dissolution Profile of Ethyl Cellulose-Theophylline Microspheres Using the Emulsion-Solvent Evaporation Process 

  Rammal, Hassan A (Lebanese American University, 2020-06-07)

  Controlled-Release drug delivery using microspheres depends on drug-encapsulation formulation, processing conditions, and excipient physical properties. Several parameters affect the microspheres’ formation and properties, ...
• Investigating the Therapeutic Effects of Small Molecule Imipridones In Pediatric Neuroblastoma 

  El Soussi, Sarra (Lebanese American University, 2020-11-19)

  The small molecule inducers of TRAIL ONC201/TIC10 and its analog ONC206 exhibit anti-tumor activity by inhibiting AKT/ERK phosphorylation and causing early activation of the integrated stress response. They are reported ...
• The role of corticosteroids in the early management of sepsis in the Lebanese population 

  El-Ratel, Rayan (Lebanese American University, 2020-12-25)

  The use of corticosteroids in the management of sepsis has been quite controversial. This thesis was motivated by a pursuit to gain a better understanding about the safety and efficacy of using corticosteroids in sepsis. ...

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