SOP - Scholarly Publications: Recent submissions

Now showing items 61-80 of 370

Evaluation of anti-inflammatory and anti-cancer activities of Lycopus uniflorus fractions

Demirdjian, SA; Hariri, EH; Mroueh, MA; Taleb, R.; Daher, CF (2018-09-06)

Lycopus uniflorus, referred to as bugleweed, is widely spread in Lebanon near freshwater wetland. The plant has been used in Lebanese folk medicine for the treatment of inflammation and gastrointestinal disorders. The ...
Antioxidant and anticancer activities of methanolic, ethyl acetate and chloroform extracts of Arum Palaestinum

Diab-Assaf, M.; Taleb, RI; Shehaby, W.; Mansour, A.; Daher, C.; Mroueh, M. (2018-09-06)

Phenolic and flavonoid contents, antioxidant and anticancer activities of the methanolic, chloroform and ethyl acetate extracts of Arum Palaestinum were evaluated. The highest phenolic (mg gallic acid equiv./g dry extract) ...
Tumorigenic proteins upregulated in the MYCN-amplified IMR-32 human neuroblastoma cells promote proliferation and migration

Zaatiti, Hayat; Abdallah, Jad; Nasr, Zeina; Khazen, George; Sandler, Anthony; Abou-Antoun, Tamara J. (2018-04-26)

Childhood neuroblastoma is one of the most common types of extra-cranial cancer affecting children with a clinical spectrum ranging from spontaneous regression to malignant and fatal progression. In order to improve the ...
Evaluation of Lycopus uniflorus water extract for anti-inflammatory, anti-ulcerogenic and antioxidant activities

Saade, S.; Ziadeh, E.; Ramia, E.; Daher, CF; Mroueh, M. (2018-04-19)

Lycopus uniflorus, commonly known as bugleweed, is usually found near freshwater wetland and has a wide abundance in Lebanon. The plant has some folk use for treatment of gastrointestinal disorders and reduction of ...
Potential anti-inflammatory, anti-ulcerogenic and antioxidant activity of Nasturtium officinalis water extract

Fares, N.; Mroueh, M.; Daher, C. (2018-04-19)

Nasturtium officinalis is a widely used edible plant in the Mediterranean region and well known for its medicinal value in folk medicine. The present study explores the effects of the water extract of N. officinalis upon ...
The effects of Cucurbita pepo seeds on testosterone induced benign prostatic hyperplasia

Nawfal, T.; Daher, C.; Mroueh, M.; Baroody, K.; Nasser, S.; Baroody, G. (2018-04-19)

The Cucurbita pepo L. (pumpkin) seeds are considered a snack food in most social gatherings in Lebanon and the Middle East. Many herbal combinations containing pumpkin seeds are used to treat symptoms of benign prostatic ...
Analysis of the pentane fraction obtained from Daucus carota oil extract and its activity against colon cancer cell lines

Taleb, RI; Chababi, W.; El-Sibai, M.; Daher, C.; Mroueh, M. (2018-04-19)

Phytotherapy has been widely used throughout the years for the treatment of a variety of diseases such as colon and colorectal cancers. Recent studies in our laboratories have shown that Daucus carota (Linnaeus) ssp. carota ...
The anti-cancer effect of the pentane fraction of Daucus carota oil extract is mediated through cell cycle arrest and an increase in apoptosis

Mroueh, MA; Shehaby, W.; Smith, K.; Karam, M.; Mansour, A.; El Asmar, M.; El-Sibai, M.; Daher, CF (2018-04-19)

Daucus carota L. ssp. carota (Apiacea) is used in traditional medicine in Lebanon and in different regions throughout the world. Previous studies from our laboratory demonstrated the in vitro anticancer activities of Daucus ...
Hepatoprotective activity of the wild carrot chloroform-based fraction against CCl4-induced liver toxicity in mice

Shebaby, W.; El-Sibai, M.; Mroueh, M.; Bodman-Smith, K.; Taleb, R.; Daher, C. (2018-04-19)

The liver plays a major role in detoxifying and clearing xenobiotics that may lead to liver damage and hepatic dysfunction. The present study was carried out to evaluate the hepatoprotective activities of the chloroform-based ...
In vivo immunomodulatory effect of wild carrot oil and its fractions

Taleb, RI; Shebaby, W.; Geha, M.; El-Sibai, M.; Mroueh, MA; Daher, CF (2018-04-19)

Daucus carota L. ssp. carota (wild carrot) oil extract (DCOE) and fractions (F1, F2, F3 and F4) were recently shown to exhibit in vitro and in vivo anticancer activity [1,2]. The aim of this study is to examine the in vivo ...
Chemopreventive potential of the pentane-based fraction of wild carrot oil against chemically-induced squamous cell carcinoma

Shebaby, W.; Daher, G.; Taleb, R.; Daaboul, H.; El Sibai, M.; Mroueh, M.; Daher, CF (2018-04-19)

Daucus carota L. ssp. carota (wild carrot) was recently shown to exhibit in vitro and in vivo anticancer activities [1, 2]. DCOE was chromatographed to yield F1 (pentane; 100%), F2 (pentane-diethyl ether; 50:50), F3 (diethyl ...
Cytotoxic effect of wild carrot oil fractions on human epidermal keratinocytes

Mroueh, M.; Shebaby, W.; El Sibai, M.; Daher, J.; Daher, CF; Taleb, RI (2018-04-19)

Wild carrot has been used in traditional medicine in Lebanon to treat several diseases. Recently, Daucus carota oil extract and its fractions, F1 (pentane; 100%), F2 (pentane-diethyl ether; 50:50), F3 (diethyl ether; 100%) ...
A new sesquiterpene from Lebanese wild carrot inhibits proliferation of human acute myeloid leukemia cells

Boulos, J.; Abi-Habib, R.; Shehaby, W.; Daher, CF; Taleb, RI; Mroueh, MA (2018-04-19)

Daucus carota L. ssp. carota (Apiaceae), also known as wild carrot, is a commonly used medicinal plant in folk medicine worldwide for the treatment of several ailments including cancer [1]. Earlier studies in our labs ...
The antitumor promoting activity of 2-himachalen-7-ol in two-stage mouse skin carcinogenesis test

Daher, CF; Iskandar, RJ; Dib El Jalbout, NO; Dwairi, VF; Zgheib, MC; Ibrahim, MC; Saad, JMC; Bakhos, PE; Chelala, NF; Daou, CP; Lteif, CS; Sawma Awad, LJ; Hakim, J.; Taleb, R.; El Sibai, M.; Mroueh, M. (2018-04-19)

Cedrus libani ssp. libani (Pinaceae) is a plant used in traditional medicine for the treatment of various diseases. 2-Himachalene-7-ol, previously isolated from the plant, possesses in vitro anticancer activity [1]. The ...
Salvia officinalis water extract: a potential hypolipidemic, hypoglycemic and anti-ulcerogenic remedy

Alayan, I.; Mroueh, M.; Daher, C. (2018-04-18)

Herbal medicine, an aspect of folk medicine, is nowadays practiced extensively in the community and most often without control when it comes to third world countries. Sage (Salvia officinalis L., Lamiaceae), widely used ...
Anti-cancer activity of 2-himachalen-7-ol isolated from Cedrus libani

Taleb, R.; El Hakim, J.; Elias, A.; Mroueh, M.; Daher, C. (2016-05-17)

Cedrus libani is among the oldest Cedrus species in the Mediterranean region. Its essential oil has been utilized in folk medicine in Lebanon and was recently shown to possess antileukemic activity [1]. The current study ...
Prevention of carcinogen-induced mouse skin papilloma by Daucus carota (wild carrot) aqueous extract

Mroueh, M.; El Ghaziri, F.; Daher, C. (2015-10-28)

Daucus carota L. ssp. carota is a part of the folk medicine in Lebanon where it is used to enhance immunity and protect against many ailments among which are inflammation, gastric ulcer, and diabetes. Earlier we reported ...
Potent anti-tumor promoting effects of Daucus carota oil extract in mice

Abou Zeinab, RM; Daher, CF; Mroueh, M. (2018-04-18)

Daucus carota, commonly known as wild carrot, is an annual or biannual herb confined to temperate regions of Europe, Asia and South Africa. In view of biochemical and pharmacological actions, it was shown that the plant ...
Anti-inflammatory effect of the methanol, ethyl acetate and chloroform extracts of Tragopogon porrifolius aerial parts

Daher, CF; Hariri, EH; El Asmar, M; Demirdjian, SA; Mroueh, MA (2018-04-18)

Tragopogon porrifolius L. (Asteraceae) is an edible plant widely used in the Lebanese folk medicine. The present study investigates the acute anti-inflammatory effect of the methanolic, ethyl acetate and chloroform extracts ...
DJ-1/PARK7 protein

Ariga, Hiroyoshi; Iguchi-Ariga, Sanae M. M. (Springer, 2017-12-21)

DJ-1 and its prokaryotic homologs, Hsp31, YhbO and YajL from Escherichia coli and PfpI from Pyrococcus furiosus, repair proteins from glycation by glyoxals (R-CO-CHO), which constitute their major glycating agents. Glycation ...

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