SOP - Scholarly Publications: Recent submissions

Now showing items 41-60 of 370

Sufi terms and their translation from Arabic to English. Diwân al-hallâ? as a case study

Affeich, Andrée; Azzam, Maya (2019-10-15)

The translation of Sufi poetry is a relatively unexplored topic. This paper examines the challenges a translator may encounter when translating Sufi terminology into English, covering the formation of Sufi terms, their ...
High-resolution bioguided screening of Ganoderma capense for P-GP modulating activity

Ta, Hp; Maciuk, A.; Vautier, S.; Milane, A.; Welti, S.; Champy, P.; Wainer, I.W.; Fernandez, C.; Figadere, B. (2019-10-15)

Ganoderma lucidum (Polyporaceae) is commonly used as a panacea e.g. in Traditional Chinese Medicine. Abundant research has shown its activity on several targets related to cancer, but no work assessed its modulating activity ...
Implementing an interprofessional education programme in Lebanon

Farra, Anna; Zeenny, Rony; Nasser, Soumana; Asmar, Nadia; Milane, Aline; Bassil, Maya; Haidar, Mona; Habre, Maha; Zeeni, Nadine; Hoffart, Nancy (2019-10-15)

Background: The Lebanese American University has a well-functioning inter-professional education (IPE) programme; this is a fundamental pedagogical approach in healthcare education in which students from different professions ...
Thrombophilic genetic anomalies and their association with dialysis initiation age in a cohort of Lebanese hemodialysis patients

Barbari, A.; Milane, A.; Salameh, P.; Abi Younes, J.; El Houjairy, A.; Safi, K.; Sabaa Ayoun, I.; Jaafar, M.; Bou Khalil, L.; Bachir, A.; Bassil, N.; Karnib, H.; Morad, N.; Rizk, S.; Masri, M. (2019-10-15)

OBJECTIVES:The relationship between chronic kidney disease and cardiovascular disease is complex and bidirectional. This relationship may be partially linked to thrombophilic genetic anomalies that may predispose to the ...
The chemotherapeutic effect of β-2-himachalen-6-ol in chemically induced skin tumorigenesis

Daaboul, Hamid E.; Dagher, Carole; Taleb, Robin I.; Bodman-Smith, Kikki; Shebaby, Wassim N.; El-Sibai, Mirvat; Mroueh, Mohamad A.; Daher, Costantine F. (2019-10-08)

β-2-himachalen-6-ol (HC), a novel sesquiterpene derived from Lebanese wild carrot, was shown to possess a remarkable anticancer activity. The present study investigates the in vitro anticancer activity of HC and its effect ...
Assessment of non-vitamin K oral anticoagulants use in a tertiary care center in the USA

Sheikh-Taha, Marwan; Deeb, Mary E. (2019-10-02)

Background Non-vitamin K oral anticoagulants (NOACs) have emerged as an attractive alternative to vitamin K antagonists for various thromboembolic indications. However, prescribed NOAC doses are often inconsistent with ...
Treatment of apixaban- and rivaroxaban-associated major bleeding using 4-factor prothrombin complex concentrate

Sheikh-Taha, Marwan (2019-10-02)

There is limited clinical experience with the use of coagulation concentrates to reverse the effect of direct oral anticoagulants. We assess the achievement of effective clinical hemostasis with the use of 4-factor prothrombin ...
Use of over the counter products in older cardiovascular patients admitted to a tertiary care center in USA

Sheikh-Taha, Marwan; Dimassi, Hani (2019-10-02)

Background In recent years there has been a substantial increase in the use of over-the-counter (OTC) products around the world. While they are assumed to be safe by consumers, they can potentially lead to adverse effects ...
Reversal of dabigatran requiring hemodialysis, fresh frozen plasma, and 2 doses of idarucizumab in a patient with acute kidney injury

Sheikh-Taha, Marwan (2019-10-02)

Purpose A case report of dabigatran-associated coagulopathy that lasted for about 1 week after drug discontinuation despite use of several treatment measures is presented. Summary Life-threatening hemorrhage can occur ...
Photoactivatable RuII Complex Bearing 2,9‐Diphenyl‐1,10‐phenanthroline: Unusual Photochemistry and Significant Potency on Cisplatin‐Resistant Cell Lines

Mansour, Najwa; Mehanna, Stephanie; Mroueh, Mohamad A.; Audi, Hassib; Bodman-Smith, Kikki; Daher, Costantine F.; Taleb, Robin I.; El-Sibai, Mirvat; Khnayzer, Rony S. (2019-10-01)

The current study investigates [Ru(bipy)2(dpphen)]Cl2 [where bipy = 2,2′‐bipyridine and dpphen = 2,9‐diphenyl‐1,10‐phenanthroline] (complex 1) for photoactivatable chemotherapy (PACT) application on five cancer cell lines. ...
Enhanced cellular uptake and photochemotherapeutic potential of a lipophilic strained Ru(II) polypyridyl complex

Mehanna, Stephanie; Mansour, Najwa; Audi, Hassib; Bodman-Smith, Kikki; Mroueh, Mohamad A.; Taleb, Robin I.; Daher, Costantine F.; Khnayzer, Rony S. (2019-10-01)

The use of ruthenium complexes as chemotherapeutic agents has been recently explored as one of the alternatives to conventional treatments. In the present study, two Ru(II) polypyridyl complexes were synthesized and ...
Ghrelin modulates intracellular signalling pathways that are critical for podocyte survival

El Zein, Nabil; Abdallah, Maya S.; Daher, Costantine F.; Mroueh, Mohammad; Stephan, Joseph; Bahous, Sola Aoun; Eid, Assaad; Faour, Wissam H. (2019-06-27)

Damage to podocytes is a key event in glomerulopathies. While energy dense food can contribute to kidney damage, the role of the orixegenic hormone “ghrelin” in podocyte biology is still unknown. In the present study, we ...
Assessment of bleeding in chronic liver disease and coagulopathy using the IMPROVE bleeding criteria

Chamoun, Nibal; Ramia, Elsy; Lteif, Christelle; Salameh, Pascale; Zantout, Hala; Ghanem, Georges; Chatila, Rajaa (2019-05-31)

Background: In this study, the authors utilized the IMPROVE (International Medical Prevention Registry on Venous Thromboembolism) bleeding definition to explore the safety profile of pharmacologic venous thromboembolism ...
Guanine glycation repair by DJ-1/Park7 and its bacterial homologs

Richarme, Gilbert; Liu, Cailing; Mihoub, Mouadh; Abdallah, Jad; Leger, Thibaut; Joly, Nicolas; Liebart, Jean-Claude; Jurkun, Ula V. (2019-05-28)

DNA damage induced by reactive carbonyls (mainly methylglyoxal and glyoxal), called DNA glycation, is quantitatively as important as oxidative damage. DNA glycation is associated with increased mutation frequency, DNA ...
Further characterization of the Maillard deglycase DJ-1 and its prokaryotic homologs, deglycase 1/Hsp31, deglycase 2/YhbO, and deglycase 3/YajL

Richarme, Gilbert; Abdallah, Jad; Mathas, Nicolas; Gautier, Valerie; Dairou, Julien (2019-05-28)

We reported recently that the Parkinsonism-associated protein DJ-1 and its bacterial homologs Hsp31, YhbO and YajL function as deglycases that repair proteins and nucleotides from endogeneous glycation by glyoxal and ...
Transforming growth factor-β1 and phosphatases modulate COX-2 protein expression and TAU phosphorylation in cultured immortalized podocytes

Abdallah, Maya S.; Kennedy, Christopher R .J.; Stephan, Joseph S.; Abou Khalil, Pamela; Mroueh, Mohammad; Eid, Assad A.; Faour, Wissam H. (2019-04-23)

Objective and design The aim of this study is to elucidate TGF-β1 signaling pathways involved in COX-2 protein induction and modulation of TAU protein phosphorylation in cultured podocytes. Materials, treatment and ...
Prevalence, correlates and management of hyperglycemia in diabetic non-critically Ill patients at a tertiary care center in Lebanon

El Khoury, Ghada; Mansour, Hanine; Kabbara, Wissam K.; Chamoun, Nibal; Atallah, Nadim; Salameh, Pascale (2019-02-20)

Background: Diabetes Mellitus is a chronic metabolic disease that affects 387 million people around the world. Episodes of hyperglycemia in hospitalized diabetic patients are associated with poor clinical outcomes and ...
Adherence to international guidelines for the treatment of uncomplicated urinary tract infections in Lebanon

Kabbara, Wissam K.; Meski, Mohamad M.; Ramadan, Wijdan H.; Maaliki, Dina S.; Salameh, Pascale (2019-02-20)

Objective. The purpose of this study is to evaluate antibiotic-prescribing practices and adherence to IDSA guidelines for the treatment of uncomplicated urinary tract infections in Lebanon. Methods. This observational ...
Patterns of pain medication use in older individuals with cardiovascular disease

Kabbara, Wissam K.; Dimassi, Hani; Sheikh-Taha, Marwan (2019-02-20)

Background: Pain is common in older adults and clinicians are often faced by many challenges when selecting appropriate treatment due to age-related changes in pharmacokinetics, pharmacodynamics, increased comorbidities, ...
Medication safety knowledge, attitudes and practices among community pharmacists in Lebanon

Hajj, Aline; Hallit, Souheil; Ramia, Elsy; Salameh, Pascale (2018-12-19)

Background: The effectiveness of a national post-marketing surveillance program depends directly on the active participation of all health professionals. There is no current comprehensive and active pharmacovigilance program ...

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