Browsing SOP - Scholarly Publications by Author "Mihoub, Mouadh"

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The DJ-1 superfamily member Hsp31 repairs proteins from glycation by methylglyoxal and glyoxal

Mihoub, Mouadh; Abdallah, Jad; Gontero, Brigitte; Dairou, Julien; Richarme, Gilberte (2016-07-19)

Hsp31 belongs to the PfpI/Hsp31/DJ-1 superfamily, and has been reported to display chaperone, peptidase and glutathione-independent glyoxalase activities. Here, we show that Hsp31 repairs glyoxal- and methylglyoxal-glycated ...
The DJ-1 superfamily members YhbO and YajL from Escherichia coli repair proteins from glycation by methylglyoxal and glyoxal

Abdallah, Jad; Mihoub, Mouadh; Gautier, Valeire; Richarme, Gilbert (2016-07-19)

YhbO and YajL belong to the PfpI/Hsp31/DJ-1 superfamily. Both proteins are involved in protection against environmental stresses. Here, we show that, like DJ-1 and Hsp31, they repair glyoxal- and methylglyoxal-glycated ...
Guanine glycation repair by DJ-1/Park7 and its bacterial homologs

Richarme, Gilbert; Liu, Cailing; Mihoub, Mouadh; Abdallah, Jad; Leger, Thibaut; Joly, Nicolas; Liebart, Jean-Claude; Jurkun, Ula V. (2019-05-28)

DNA damage induced by reactive carbonyls (mainly methylglyoxal and glyoxal), called DNA glycation, is quantitatively as important as oxidative damage. DNA glycation is associated with increased mutation frequency, DNA ...

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