Browsing SOP - Scholarly Publications by Author "El-Sibai, Mirvat"

Now showing items 1-13 of 13

ALOX5AP gene variants show differential association with coronary artery disease in different populations

Alwan, Ahmad; Youhanna, Sonia C.; Platt, Daniel E.; El-Sibai, Mirvat; Yerezian, Joumana S.; Deeb, Mary E.; Khazen, Georges; Saade, Stephanie; Zreik, Tony G.; El Bayeh, Hamid; Maalouf, Assaad; Zalloua, Pierre A.; Abchee, Antoine (2015-12-17)

Coronary artery disease (CAD) is a complex disease with various components, genetic as well as environmental. Previous reports correlating ALOX5AP gene variants and CAD showed conflicting results depending on the population ...
The antioxidant and anticancer effects of Wild Carrot oil extract

Shebaby, Wassim Nasri; El-Sibai, Mirvat; Bodman-Smith, Kikki; Karam, Marc Christoph; Mroueh, Mohamad; Daher, Costantine F. (2015-11-04)

Daucus carota L. ssp. carota (Apiacea) is used in traditional medicine in Lebanon and in different regions throughout the world. The present study investigates the in vitro anticancer activities of Daucus carota oil extract ...
Antioxidant and hepatoprotective activities of the oil fractions from wild carrot (Daucus carota ssp. carota)

Shebaby, Wassim N.; Daher, Costantine F.; El-Sibai, Mirvat; Bodman-Smith, Kikki; Mansour, Anthony; Karam, Marc C.; Mroueh, Mohamad (2015-12-16)

Context: Wild carrot, Daucus carota L. ssp. carota (Apiacae), is widely distributed throughout the world and has various uses in traditional medicine in Lebanon. Objective: The present study aimed to fractionate and ...
Antitumor activity of β-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways

Daaboul, Hamid E.; Daher, Costantine F.; Bodman-Smith, Kikki; Taleb, Robin I.; Shehaby, Wassim N.; Boulos, Joelle; Dagher, Carole; Mroueh, Mohamad A.; El-Sibai, Mirvat (2017-12-15)

Previous studies in our laboratory showed that Daucus carota oil extract (DCOE) possesses in vitro and in vivo anticancer activities. Chemical analysis of DCOE led to the isolation of β-2-himachalen-6-ol (HC) which exhibited ...
The chemotherapeutic effect of β-2-himachalen-6-ol in chemically induced skin tumorigenesis

Daaboul, Hamid E.; Dagher, Carole; Taleb, Robin I.; Bodman-Smith, Kikki; Shebaby, Wassim N.; El-Sibai, Mirvat; Mroueh, Mohamad A.; Daher, Costantine F. (2019-10-08)

β-2-himachalen-6-ol (HC), a novel sesquiterpene derived from Lebanese wild carrot, was shown to possess a remarkable anticancer activity. The present study investigates the in vitro anticancer activity of HC and its effect ...
Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells

Shebaby, Wassim N.; Mroueh, Mohammad; Bodman-Smith, Kikki; Mansour, Anthony; Taleb, Robin I.; Daher, Costantine F.; El-Sibai, Mirvat (2016-05-16)

Background Daucus carota L.ssp.carota (wild carrot), an herb used in folk medicine worldwide, was recently demonstrated to exhibit anticancer activity. In this study we examined the anticancer effect of Daucus carota oil ...
Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways

Shehaby, Wassim N.; Bodman-Smith, K.B.; Mansour, Anthony; Mroueh, Mohamad; Taleb, Robin I.; El-Sibai, Mirvat; Daher, Costantine F. (2015-12-17)

Daucus carota L. ssp. carota (Apiacea, wild carrot, Queen Anne's lace) has been used in folk medicine throughout the world and recently was shown to possess anticancer and antioxidant activities. This study aims to determine ...
Daucus carota pentane/diethyl ether fraction inhibits motility and reduces invasion of cancer cells

Zgheib, Perla; Daher, Costantine F.; Mroueh, Mohamad; Nasrallah, Anita; Taleb, Robin I.; El-Sibai, Mirvat (2017-02-08)

Daucus carota (DC) is a herb used in folklore medicine in Lebanon to treat numerous diseases including cancer. Recent studies in our laboratory on DC oil and its fractions revealed potent anticancer activities in vitro and ...
Hepatoprotective, Antioxidant, and Anticancer Effects of the Tragopogon porrifolius Methanolic Extract

Tenkerian, Clara; El-Sibai, Mirvat; Daher, Costantine F.; Mroueh, Mohamad (2015-12-16)

Tragopogon porrifolius (Asteraceae), commonly referred to as white salsify, is an edible herb used in Lebanese folk medicine to treat cancer and liver dysfunction. In this study, we investigated the antioxidant activity ...
Photoactivatable RuII Complex Bearing 2,9‐Diphenyl‐1,10‐phenanthroline: Unusual Photochemistry and Significant Potency on Cisplatin‐Resistant Cell Lines

Mansour, Najwa; Mehanna, Stephanie; Mroueh, Mohamad A.; Audi, Hassib; Bodman-Smith, Kikki; Daher, Costantine F.; Taleb, Robin I.; El-Sibai, Mirvat; Khnayzer, Rony S. (2019-10-01)

The current study investigates [Ru(bipy)2(dpphen)]Cl2 [where bipy = 2,2′‐bipyridine and dpphen = 2,9‐diphenyl‐1,10‐phenanthroline] (complex 1) for photoactivatable chemotherapy (PACT) application on five cancer cell lines. ...
Wild carrot pentane-based fractions suppress proliferation of human HaCaT keratinocytes and protect against chemically-induced skin cancer

Shebaby, Wassim N.; Mroueh, Mohamad A.; Boukamp, Petra; Bodman-Smith, Kikki; Ishac Taleb, Robin; El-Sibai, Mirvat; Daher, Costantine F. (2017-03-14)

Background Previous studies in our laboratory showed that the Lebanese Daucus carota ssp. carota (wild carrot) oil extract possesses in vitro and in vivo anticancer activities. The present study aims to examine the cytotoxic ...
β-2-himachalen-6-ol

Taleb, Robin I.; Najm, Paul; Shebaby, Wassim; Boulos, Joelle C.; Demirdjian, Sally; Hariri, Essa; El-Sibai, Mirvat; Daher, Costantine; Mroueh, Mohamad (2016-10-13)

Daucus carota ssp. carota, also known as wild carrot, is a commonly used herb in Lebanese folk medicine to treat several ailments including cancer. Previous studies in our laboratories showed that the Daucus carota oil ...
β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo

Daaboul, Hamid E.; Daher, Costantine F.; Taleb, Robin I.; Boulos, Joelle; Bodman‐Smith, Kikki; Boukamp, Petra; Shebaby, Wassim N.; Dagher, Carol; El-Sibai, Mirvat; Mroueh, Mohamad A. (2017-12-15)

Background Previous studies in our laboratory showed that Daucus carota oil extract (DCOE) possesses remarkable in-vitro anticancer activity and antitumour promoting effect against DMBA/TPA skin carcinogenesis in mice. ...

Now showing items 1-13 of 13

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