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Browsing SOP - Scholarly Publications by Title

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Browsing SOP - Scholarly Publications by Title

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  • Brain cancer stem cells in adults and children 
    Abou-Antoun, Tamara J.; Hale, James S.; Lathia, Justin D.; Dombrowski, Stephen M. (2017-12-18)
    Brain tumors represent some of the most malignant cancers in both children and adults. Current treatment options target the majority of tumor cells but do not adequately target self-renewing cancer stem cells (CSCs). CSCs ...
  • Branched-Chain Amino Acids in Patients With Hepatic Encephalopathy 
    Btaiche, Imad F. (2016-10-06)
    Hospitalized patients with hepatic insufficiency often suffer from severe catabolic states and are in urgent need of nutrition support during their acute illness. Protein intolerance, however, remains a significant problem ...
  • Breathing frequency (fR) is no longer under chemoreflex control during REM sleep 
    Burke, Peter; Kanbar, Roy; Basrting, Tyler; Viar, Kenneth; Stornetta, Ruth; Guyenet, Patrice (2016-10-11)
    Objective: To define the contribution of central chemoreception in general and the retrotrapezoid nucleus (RTN) in particular to the regulation of breathing in REM sleep. Methods: EEG, neck EMG, blood pressure, fR and tidal ...
  • Breathing regulation and blood gas homeostasis after near complete lesions of the retrotrapezoid nucleus in adult rats 
    Souza, George M.P.; Kanbar, Roy; Stornetta, Daniel S.; Abbott, Stephen B.G.; Stornetta, Ruth L.; Guyenet, Patrice G. (2019-10-17)
    The retrotrapezoid nucleus (RTN) is one of several CNS nuclei that contribute, in various capacities (e.g. CO2 detection, neuronal modulation) to the central respiratory chemoreflex (CRC). Here we test how important the ...
  • Buccal Cell DNA Extraction 
    Saab, Yolande B.; Kabbara, Wissam; Chebib, Christiane; Gard, Paul Richard (2016-09-26)
    Simple and cost-effective methods are needed to extract DNA in order to use it in large-scale studies. Blood is an excellent DNA source; however, it is costly and invasive thus an alternative is needed. Several kits and ...
  • C1 neurons excite locus coeruleus and A5 noradrenergic neurons along with sympathetic outflow in rats 
    Abbott, S. B.; Kanbar, R.; Bochorishvili, G.; Coates, M. B.; Stornetta, R. L.; Guyenet, P. G. (2016-10-11)
    C1 neurons activate sympathetic tone and stimulate the hypothalamic–pituitary–adrenal axis in circumstances such as pain, hypoxia or hypotension. They also innervatepontine noradrenergic cell groups, including the locus ...
  • Cafeteria diet-fed mice is a pertinent model of obesity-induced organ damage 
    Zeeni, Nadine; Dimassi, Hani; Faour, Wissam H.; Dagher-Hamalian, Carole (2017-02-28)
    Objective This study is aimed at evaluating the effects of a cafeteria diet (obesity) mouse model on early multi-organ functional, structural, endocrine and biochemical alterations. Materials and methods Multi-organ ...
  • Cancer cell resistance mechanisms 
    Al-Dimassi, S.; Abou-Antoun, T.; El-Sibai, M. (2015-12-18)
    Cancer is a leading cause of death worldwide accounting to 13 % of all deaths. One of the main causes behind the failure of treatment is the development of various therapy resistance mechanisms by the cancer cells leading ...
  • Cancer stem cells in neuroblastoma 
    Bahmad, Hisham F.; Chamaa, Farah; Assi, Sahar; Chalhoub, Reda M.; Abou-Antoun, Tamara; Abou-Kheir, Wassim (2019-11-07)
    Neuroblastoma (NB) is the most common extracranial solid tumor often diagnosed in childhood. Despite intense efforts to develop a successful treatment, current available therapies are still challenged by high rates of ...
  • The Candida albicans Hwp2 is necessary for proper adhesion, biofilm formation and oxidative stress tolerance 
    Dimassi, Hani I.; Khalaf, Roy A.; Younes, Samer; Bahnan, Wael (2015-09-30)
    Candida albicans is an important fungal pathogen of humans that is responsible for the majority of mucosal and systemic candidiasis. The host–pathogen interaction in C. albicans has been the subject of intense investigation ...
  • Carcinogenic and neurotoxic risks of acrylamide and heavy metals from potato and corn chips consumed by the Lebanese population 
    Hariri, Essa; Abboud, Martine I.; Demerdjian, Sally; Korfali, Samira; Mroueh, Mohamad; Taleb, Robin I. (2016-10-13)
    The present study aims to quantify acrylamide and metals in potato and corn chips and to determine their carcinogenic and neurotoxic risks. Gas chromatography mass spectrometry analysis revealed that the average acrylamide ...
  • Central CO2 chemoreception and integrated neural mechanisms of cardiovascular and respiratory control 
    Guyenet, Patrice G.; Stornetta, Ruth L.; Abbott, Stephen B.G.; Depuy, Seth D.; Fortuna, Michal G.; Kanbar, Roy (2016-10-10)
    In this review, we examine why blood pressure (BP) and sympathetic nerve activity (SNA) increase during a rise in central nervous system (CNS) Pco2 (central chemoreceptor stimulation). CNS acidification modifies SNA by two ...
  • Cethromycin 
    Mansour, Hanine; Chahine, Elias B.; Karaoui, Lamis R.; El-Lababidi, Rania M. (2016-09-29)
    OBJECTIVE To review the pharmacology, chemistry, microbiology, in vitro susceptibility, mechanism of resistance, pharmacokinetics, pharmacodynamics, clinical efficacy, safety, drug interactions, dosage, and administration ...
  • Challenges of recruiting american minority graduate students 
    Capomacchia, Anthony C.; Graner, Solomon T. (2017-10-18)
    Objectives. To examine the Coach Model for recruiting minority students for the pharmaceutical and biomedical sciences at the University of Georgia College of Pharmacy. The long-term goal is to establish the University of ...
  • Characterisation of Pga1, a putative Candida albicans cell wall protein necessary for proper adhesion and biofilm formation 
    Malouf, Katia; Dimassi, Hani I.; Khalaf, Roy A.; Hashash, Rami; Younes, Samer; Bahnan, Wael; El-Koussa, Joseph (2015-09-30)
    The fungal pathogen Candida albicans is a leading causative agent of death in immunocompromised individuals. Many factors have been implicated in virulence including filamentation-inducing transcription factors, adhesins, ...
  • Characterization of the Escherichia coli YedU protein as a molecular chaperone 
    Malki, Abderrahim; Kern, Renee; Abdallah, Jad; Richarme, Gilbert (2016-07-19)
    We have cloned, purified to homogeneity, and characterized as a molecular chaperone the Escherichia coli YedU protein. The purified protein shows a single band at 31 kDa on SDS–polyacrylamide gels and forms dimers in ...
  • Chemopreventive effects of wild carrot oil against 7,12-dimethyl benz(a)anthracene-induced squamous cell carcinoma in mice 
    Abu Zeinab, Rami; Mroueh, Mohamad; Diab-Assaf, Mona; Jurjus, Abdo; Wex, Brigitte; Sakr, Amer; Daher, Costantine F. (2015-12-01)
    Context: Daucus carota L. ssp. carota (Apiacea) is widely distributed throughout the world and has many uses in traditional medicine. Objective: The present study investigates the chemopreventive effects of oil extract ...
  • Chemopreventive potential of the pentane-based fraction of wild carrot oil against chemically-induced squamous cell carcinoma 
    Shebaby, W.; Daher, G.; Taleb, R.; Daaboul, H.; El Sibai, M.; Mroueh, M.; Daher, CF (2018-04-19)
    Daucus carota L. ssp. carota (wild carrot) was recently shown to exhibit in vitro and in vivo anticancer activities [1, 2]. DCOE was chromatographed to yield F1 (pentane; 100%), F2 (pentane-diethyl ether; 50:50), F3 (diethyl ...
  • The chemotherapeutic effect of β-2-himachalen-6-ol in chemically induced skin tumorigenesis 
    Daaboul, Hamid E.; Dagher, Carole; Taleb, Robin I.; Bodman-Smith, Kikki; Shebaby, Wassim N.; El-Sibai, Mirvat; Mroueh, Mohamad A.; Daher, Costantine F. (2019-10-08)
    β-2-himachalen-6-ol (HC), a novel sesquiterpene derived from Lebanese wild carrot, was shown to possess a remarkable anticancer activity. The present study investigates the in vitro anticancer activity of HC and its effect ...
  • Clinical and cost impact of intravenous proton pump inhibitor use in non-ICU patients 
    Nasser, Soumana C.; Dimassi, Hani I.; Nassif, Jeanette G. (2015-10-01)
    AIM: To assess the appropriateness of the indication and route of administration of proton-pump-inhibitors (PPIs) and their associated cost impact. METHODS: Data collection was performed prospectively during a 6-mo ...

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