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Browsing SOP - Scholarly Publications by Title

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Browsing SOP - Scholarly Publications by Title

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  • Bedaquiline 
    Chahine, Elias B.; Karaoui, Lamis R.; Mansour, Hanine (2016-09-29)
    Objective: To review the chemistry, pharmacology, microbiology, pharmacokinetics, pharmacodynamics, clinical efficacy, safety, dosage, and administration of bedaquiline, a novel oral diarylquinoline antimycobacterial agent ...
  • Binding of 3-aminoacridinium and 7-aminoquinolinium monocations to double-stranded DNA 
    Capomacchia, Anthony C.; Schulman, Stephen G. (2017-10-18)
    The complexations of the singly charged cations of 3-aminoacridine and 7-aminoquinoline by double-stranded, calf thymus DNA were studied by electronic absorption spectrophotometry. At high ratios of total DNA phosphate ...
  • Bioequivalence of losartan/amlodipine fixed dose combination tablets (losanet AM) compared with concomitant administration of Single components of losartan and amlodipine tablets in healthy human volunteers 
    Bustami, Rana; Khasawneh, Sewar; Absi, Wafaa; Feddah, Hamzeh; Mroueh, Mohamad; Daccache, Elie; Sarraf, Jean-Charles; Kyriacos, Soula (2017-12-15)
    A fixed dose combination of losartan, an angiotensin receptor blocker and amlodipine, a calcium channel blocker, can potentially provide complementary mechanism of action to improve blood pressure control and clinical outcomes. ...
  • Brain and plasma riluzole pharmacokinetics 
    Milane, Aline; Tortolano, Lionel; Fernadez, Christine; Bensimon, Gilbert; Meininger, Vincent; Farinotti, Robert (2016-10-04)
    Purpose. Amyotrophic lateral sclerosis is a fatal neurodegenerative disease characterized by the loss of motorneurons. The only drug approved is riluzole. Minocycline is an antibiotic with numerous neuroprotective ...
  • Brain cancer stem cells in adults and children 
    Abou-Antoun, Tamara J.; Hale, James S.; Lathia, Justin D.; Dombrowski, Stephen M. (2017-12-18)
    Brain tumors represent some of the most malignant cancers in both children and adults. Current treatment options target the majority of tumor cells but do not adequately target self-renewing cancer stem cells (CSCs). CSCs ...
  • Branched-Chain Amino Acids in Patients With Hepatic Encephalopathy 
    Btaiche, Imad F. (2016-10-06)
    Hospitalized patients with hepatic insufficiency often suffer from severe catabolic states and are in urgent need of nutrition support during their acute illness. Protein intolerance, however, remains a significant problem ...
  • Breathing frequency (fR) is no longer under chemoreflex control during REM sleep 
    Burke, Peter; Kanbar, Roy; Basrting, Tyler; Viar, Kenneth; Stornetta, Ruth; Guyenet, Patrice (2016-10-11)
    Objective: To define the contribution of central chemoreception in general and the retrotrapezoid nucleus (RTN) in particular to the regulation of breathing in REM sleep. Methods: EEG, neck EMG, blood pressure, fR and tidal ...
  • Breathing regulation and blood gas homeostasis after near complete lesions of the retrotrapezoid nucleus in adult rats 
    Souza, George M.P.; Kanbar, Roy; Stornetta, Daniel S.; Abbott, Stephen B.G.; Stornetta, Ruth L.; Guyenet, Patrice G. (2019-10-17)
    The retrotrapezoid nucleus (RTN) is one of several CNS nuclei that contribute, in various capacities (e.g. CO2 detection, neuronal modulation) to the central respiratory chemoreflex (CRC). Here we test how important the ...
  • Buccal Cell DNA Extraction 
    Saab, Yolande B.; Kabbara, Wissam; Chebib, Christiane; Gard, Paul Richard (2016-09-26)
    Simple and cost-effective methods are needed to extract DNA in order to use it in large-scale studies. Blood is an excellent DNA source; however, it is costly and invasive thus an alternative is needed. Several kits and ...
  • C1 neurons excite locus coeruleus and A5 noradrenergic neurons along with sympathetic outflow in rats 
    Abbott, S. B.; Kanbar, R.; Bochorishvili, G.; Coates, M. B.; Stornetta, R. L.; Guyenet, P. G. (2016-10-11)
    C1 neurons activate sympathetic tone and stimulate the hypothalamic–pituitary–adrenal axis in circumstances such as pain, hypoxia or hypotension. They also innervatepontine noradrenergic cell groups, including the locus ...
  • Cafeteria diet-fed mice is a pertinent model of obesity-induced organ damage 
    Zeeni, Nadine; Dimassi, Hani; Faour, Wissam H.; Dagher-Hamalian, Carole (2017-02-28)
    Objective This study is aimed at evaluating the effects of a cafeteria diet (obesity) mouse model on early multi-organ functional, structural, endocrine and biochemical alterations. Materials and methods Multi-organ ...
  • Cancer cell resistance mechanisms 
    Al-Dimassi, S.; Abou-Antoun, T.; El-Sibai, M. (2015-12-18)
    Cancer is a leading cause of death worldwide accounting to 13 % of all deaths. One of the main causes behind the failure of treatment is the development of various therapy resistance mechanisms by the cancer cells leading ...
  • Cancer stem cells in neuroblastoma 
    Bahmad, Hisham F.; Chamaa, Farah; Assi, Sahar; Chalhoub, Reda M.; Abou-Antoun, Tamara; Abou-Kheir, Wassim (2019-11-07)
    Neuroblastoma (NB) is the most common extracranial solid tumor often diagnosed in childhood. Despite intense efforts to develop a successful treatment, current available therapies are still challenged by high rates of ...
  • The Candida albicans Hwp2 is necessary for proper adhesion, biofilm formation and oxidative stress tolerance 
    Dimassi, Hani I.; Khalaf, Roy A.; Younes, Samer; Bahnan, Wael (2015-09-30)
    Candida albicans is an important fungal pathogen of humans that is responsible for the majority of mucosal and systemic candidiasis. The host–pathogen interaction in C. albicans has been the subject of intense investigation ...
  • Carcinogenic and neurotoxic risks of acrylamide and heavy metals from potato and corn chips consumed by the Lebanese population 
    Hariri, Essa; Abboud, Martine I.; Demerdjian, Sally; Korfali, Samira; Mroueh, Mohamad; Taleb, Robin I. (2016-10-13)
    The present study aims to quantify acrylamide and metals in potato and corn chips and to determine their carcinogenic and neurotoxic risks. Gas chromatography mass spectrometry analysis revealed that the average acrylamide ...
  • Central CO2 chemoreception and integrated neural mechanisms of cardiovascular and respiratory control 
    Guyenet, Patrice G.; Stornetta, Ruth L.; Abbott, Stephen B.G.; Depuy, Seth D.; Fortuna, Michal G.; Kanbar, Roy (2016-10-10)
    In this review, we examine why blood pressure (BP) and sympathetic nerve activity (SNA) increase during a rise in central nervous system (CNS) Pco2 (central chemoreceptor stimulation). CNS acidification modifies SNA by two ...
  • Cethromycin 
    Mansour, Hanine; Chahine, Elias B.; Karaoui, Lamis R.; El-Lababidi, Rania M. (2016-09-29)
    OBJECTIVE To review the pharmacology, chemistry, microbiology, in vitro susceptibility, mechanism of resistance, pharmacokinetics, pharmacodynamics, clinical efficacy, safety, drug interactions, dosage, and administration ...
  • Challenges of recruiting american minority graduate students 
    Capomacchia, Anthony C.; Graner, Solomon T. (2017-10-18)
    Objectives. To examine the Coach Model for recruiting minority students for the pharmaceutical and biomedical sciences at the University of Georgia College of Pharmacy. The long-term goal is to establish the University of ...
  • Characterisation of Pga1, a putative Candida albicans cell wall protein necessary for proper adhesion and biofilm formation 
    Malouf, Katia; Dimassi, Hani I.; Khalaf, Roy A.; Hashash, Rami; Younes, Samer; Bahnan, Wael; El-Koussa, Joseph (2015-09-30)
    The fungal pathogen Candida albicans is a leading causative agent of death in immunocompromised individuals. Many factors have been implicated in virulence including filamentation-inducing transcription factors, adhesins, ...
  • Characterization of the Escherichia coli YedU protein as a molecular chaperone 
    Malki, Abderrahim; Kern, Renee; Abdallah, Jad; Richarme, Gilbert (2016-07-19)
    We have cloned, purified to homogeneity, and characterized as a molecular chaperone the Escherichia coli YedU protein. The purified protein shows a single band at 31 kDa on SDS–polyacrylamide gels and forms dimers in ...

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