Purpose. The mechanism of action, pharmacokinetics, pharmacodynamics, and clinical efficacy and safety of an investigational second-generation oxazolidinone are reviewed. Summary. Tedizolid is a protein synthesis inhibitor ...

Escherichia coli contains two thioredoxins, Trx1 and Trx2, and a thioredoxin-like protein, YbbN, which presents a strong homology in its N-terminal part with thioredoxins, and possesses a 20 kDa C-terminal part of unknown ...

In the development of the extraction procedure for the analysis of nicotine and cotinine from a single breast milk sample, nicotine and cotinine were detected in 3 of 10 nonsmoking mothers' milk samples. Interviews of these ...

Background. Continuous renal replacement therapy (CRRT) increasingly is being used to treat critically ill patients with renal disease. CRRT removes waste products but also nutrients. Our understanding of trace element ...

Background : Transcatheter aortic valve implantation(TAVI) has recently emerged as a therapeuticalternative for high-risk surgical patients with severe symptomaticaortic valve stenosis and has been shown to improveclinical ...

This study examined the possible influence of changes in heart rate (HR) on the gain of the transfer function relating renal sympathetic nerve activity (RSNA) to arterial pressure (AP) at HR frequency in rats. In seven ...

Objective and design The aim of this study is to elucidate TGF-β1 signaling pathways involved in COX-2 protein induction and modulation of TAU protein phosphorylation in cultured podocytes. Materials, treatment and ...

There is limited clinical experience with the use of coagulation concentrates to reverse the effect of direct oral anticoagulants. We assess the achievement of effective clinical hemostasis with the use of 4-factor prothrombin ...

Introduction. The available studies on the treatment of mental disorders in the Arab world are uncommon. Methods. A literature review was conducted aiming at identifying studies related to the rate and type of treatment ...

Acetaminophen (APAP), also known as paracetamol, is used by millions of people worldwide for its antipyretic and analgesic properties. At therapeutic doses, APAP is effective and safe. However, the long-term use and the ...